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Details for Product No. ABIN151297

RAD51 Homolog C (S. Cerevisiae) (RAD51C) antibody

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Synonyms BROVCA3, FANCO, R51H3, RAD51L2, Rad51l2, RGD1563765, ATRAD51C, F4L23.21, RAS associated with diabetes protein 51C, CG2412, Dm CG2412, Dmel\\CG2412, zgc:101596, RAD51C, Rad51c
»Alternatives Human, Monkey, Mouse (Murine)
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB)
Pubmed 6 references available
Catalog no. ABIN151297
Quantity 0.1 mL
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Immunogen His-tagged human Rad51C, over-expressed in E. coli.
Clone 2H11-6
Isotype IgG1
Specificity This antibody is specific for Rad51C. Species Reactivity: ABIN151297 recognizes human and mouse Rad51C. Other species have not beentested.ABIN151297 does not cross-react with Rad51B, Rad51D, Rad51, XRCC2, or XRCC3 inWestern analysis. Localization: Nuclear.
Cross-Reactivity Human
Purification Ascites
Alternative Name RAD51C
Background The Rad51 DNA repair protein is a key component of the double-strand break repairpathway and is essential for mitotic and meiotic recombination and genomic stability.Five human Rad51 homologs have been identified: XRCC2, XRCC3, Rad51B, Rad51C,and Rad51D. Each of these homologs interacts with one or more of the others, with allof the proteins involved in one complex, or with multiple smaller complexes. Alternate Names: anti-DNA repair protein Rad51 homolog 3 antibody, anti-Rad51 homolog C (S.cerevisiae) antibody, anti-Rad51L2 antibody, anti-Yeast Rad51 homolog 3 antibody.
Gene ID 5889, 114714
Application Notes Suggested working dilutions: Western Blot 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/ml
Buffer PBS (physiological pH). Preservative: 0.02% sodium azide.
Preservative Sodium azide
Storage 4 °C
Masson, Tarsounas, Stasiak et al.: "Identification and purification of two distinct complexes containing the five RAD51 paralogs." in: Genes & development, Vol. 15, Issue 24, pp. 3296-307, 2001 (PubMed).

Maacke, Hundertmark, Miska et al.: "Autoantibodies in sera of pancreatic cancer patients identify recombination factor Rad51 as a tumour-associated antigen." in: Journal of cancer research and clinical oncology, Vol. 128, Issue 4, pp. 219-22, 2002 (PubMed).

Fan, Kumaravel, Jalali et al.: "Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression." in: Cancer research, Vol. 64, Issue 23, pp. 8526-33, 2004 (PubMed).

Kuznetsov, Pellegrini, Shuda et al.: "RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females." in: The Journal of cell biology, Vol. 176, Issue 5, pp. 581-92, 2007 (PubMed).

Chan, Koritzinsky, Zhao et al.: "Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance." in: Cancer research, Vol. 68, Issue 2, pp. 605-14, 2008 (PubMed).

Shammas, Shmookler Reis, Koley et al.: "Dysfunctional homologous recombination mediates genomic instability and progression in myeloma." in: Blood, Vol. 113, Issue 10, pp. 2290-7, 2009 (PubMed).

Alternatives for antigen "RAD51 Homolog C (S. Cerevisiae) (RAD51C)", type "Antibodies"
Hosts (31), (18), (8)
Reactivities (55), (15), (12), (12), (12), (12), (1)
Applications (45), (18), (10), (5), (5), (2), (2), (1), (1), (1), (1)
Conjugates (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (4), (3), (2), (2), (2), (1), (1), (1), (1)