Cadherin Pan antibody

Details for Product No. ABIN151404
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Antigen
Reactivity
Cow (Bovine)
(8), (4), (4), (3)
Host
Mouse
(11), (1)
Clonality (Clone)
Monoclonal ()
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(8), (5), (4), (4), (2)
Pubmed 2 references available
Catalog no. ABIN151404
Quantity 0.1 mL
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Immunogen Synthetic peptide: DYDYLNDWGPRFKKLADMYGGGDD conjugated to KLH,corresponding to 24 amino acids 889-912 of Chicken N-Cadherin (cdh2).
Clone CH-19
Isotype IgG1
Specificity Reacts with all cadherins. The cadherins migrate in the molecular weight range of 125 to140 kDa and are tissue dependent. Species Reactivity: Cross-reacts with Human, Mouse, Rat, Cat, Chicken, Cow, Dog, Goat, Guinea Pig,Hamster, Pig, Psammoys (sand rat), Rabbit, Sheep, Snake and Xenopus. Not yet testedin other species. Localization: Cell membrane.
Cross-Reactivity Cow (Bovine), Dog (Canine), Chicken, Cat (Feline), Guinea Pig, Hamster, Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine), Xenopus laevis
Purification Ascites
Alternative Name Cadherin (pan)
Background Cadherins are members of a multigene family of single chain glycoprotein receptorsmediating Ca2+-dependent cell-cell adhesion.1,2,3 The N-terminal part of thesemolecules is exposed on the external cell surface and contains the putative homophilicbinding sites. This is followed by a typical single transmembrane sequence and usuallya cytoplasmic C-terminal tail which mediates interaction with the microfilament systemthrough molecules such as catenins, plakoglobin, vinculin, and.
Gene ID 1000, 83502
Research Area Extracellular Matrix, Signaling, Cytoskeleton
Application Notes Suggested working dilutions: Western Blot 1/1000,Immunohistochemistry-Paraffin 1/500,Immunohistochemistry-Frozen
Restrictions For Research Use only
Format Liquid
Concentration 6.6 mg/ml
Buffer Ascitic fluid. Preservative: Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
anti-Cadherin Pan antibody Monoclonal Anti-Pan Cadherin antibody produced in mouse
General Takeichi: "Cadherins: a molecular family important in selective cell-cell adhesion." in: Annual review of biochemistry, Vol. 59, pp. 237-52, 1990 (PubMed).

Orthmann-Murphy, Salsano, Abrams et al.: "Hereditary spastic paraplegia is a novel phenotype for GJA12/GJC2 mutations." in: Brain : a journal of neurology, Vol. 132, Issue Pt 2, pp. 426-38, 2009 (PubMed).

Hosts (11), (1)
Reactivities (8), (4), (4), (3)
Applications (8), (5), (4), (4), (2)
Epitopes (2)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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