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Details for Product No. ABIN151423

Abnormal DAuer Formation Family Member (Daf-3) (DAF-3) antibody

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»Alternatives Caenorhabditis elegans (C. elegans)
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN151423
Quantity 0.1 mL
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Immunogen A synthetic peptide made to the C-terminus (within residues 700-796) of the C.elegansDAF-3 protein.
Specificity Species Reactivity: ABIN151423 can be used to detect C. elegans DAF-3 protein. Localization: Nuclear.
Cross-Reactivity Caenorhabditis elegans (C. elegans)
Purification Serum
Alternative Name DAF-3
Background Signals from TGF-beta superfamily receptors are transduced to the nucleus by Smadproteins, which transcriptionally activate target genes. In Caenorhabditis elegans(C.elegans), defects in a TGF-beta-related pathway cause a reversible developmentalarrest and metabolic shift at the dauer larval stage. DAF-3 transgenes interfere withdauer formation, playing a role in the nucleus. DAF-3 is unique in that it is antagonized,rather than activated, by a TGF-beta pathway. Alternate Names: anti-Abnormal dauer formation protein 3 antibody, anti-isoform c antibody, anti-DAF3antibody, anti-DAF 3 antibody.
UniProt O17532
Application Notes Western Blot 1:1,000-1:5,000
Restrictions For Research Use only
Format Liquid
Buffer Preservative: 0.05% sodium azide.
Preservative Sodium azide
Storage -20 °C
Deplancke, Mukhopadhyay, Ao et al.: "A gene-centered C. elegans protein-DNA interaction network." in: Cell, Vol. 125, Issue 6, pp. 1193-205, 2006 (PubMed).

Alternatives for antigen "Abnormal DAuer Formation Family Member (Daf-3) (DAF-3)", type "Antibodies"
Hosts (4)
Reactivities (4), (1)
Applications (4), (3), (3)
Epitopes (2)