DAF3 antibody

Antigen: DAF3

Clonality: Polyclonal

Host: Rabbit

Reactivity: Caenorhabditis elegans (C. elegans)

Application: Immunoprecipitation (IP), Western Blotting (WB)

Catalog no.: ABIN151423

Additional Information

Alternative name: DAF-3

UniProt: O17532

Immunogen: A synthetic peptide made to the C-terminus (within residues 700-796) of the C.elegansDAF-3 protein.

Cross-Reactivity: Caenorhabditis elegans (C. elegans)

Format: Serum

Description: Signals from TGF-beta superfamily receptors are transduced to the nucleus by Smadproteins, which transcriptionally activate target genes. In Caenorhabditis elegans(C.elegans), defects in a TGF-beta-related pathway cause a reversible developmentalarrest and metabolic shift at the dauer larval stage. DAF-3 transgenes interfere withdauer formation, playing a role in the nucleus. DAF-3 is unique in that it is antagonized,rather than activated, by a TGF-beta pathway. Alternate Names: anti-Abnormal dauer formation protein 3 antibody, anti-isoform c antibody, anti-DAF3antibody, anti-DAF 3 antibody.

Specificity: Species Reactivity: ABIN151423 can be used to detect C. elegans DAF-3 protein. Localization: Nuclear.

Application Details

Application Notes: Western Blot 1:1,000-1:5,000

Purification: Serum

Buffer: Preservative: 0.05% sodium azide.

Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Restrictions: For Research Use only

Images

anti-DAF3 antibody

Publications

Deplancke, Mukhopadhyay, Ao et al.: "A gene-centered C. elegans protein-DNA interaction network." in: Cell, Vol. 125, Issue 6, pp. 1193-205, 2006 (PubMed).