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DBN1 antibody (Drebrin 1)

Details for Product anti-DBN1 Antibody No. ABIN151450, Supplier: Log in to see
Antigen
  • D0S117E
  • DBN1
  • LOC733967
Reactivity
Cow (Bovine), Chicken, Cat (Feline), Human, Mouse (Murine), Rabbit, Rat (Rattus)
78
27
25
6
4
3
Host
Mouse
38
35
10
1
Clonality (Clone)
Monoclonal ()
Conjugate
This DBN1 antibody is un-conjugated
6
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
64
23
20
18
17
14
12
11
9
8
1
1
Supplier
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Immunogen Chicken Drebrin E protein.
Clone M2F6
Isotype IgG1
Cross-Reactivity (Details) Not yet tested in other species.
Purification Protein A purified
Alternative Name Drebrin 1 (DBN1 Antibody Abstract)
Background Gene Symbol: DBN1
Gene ID 1627, 56320, 81653
UniProt P18302
Application Notes Western Blot 1 μg/mL, Immunohistochemistry 10 μg/mL, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin 10 μg/mL
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS with 50 % glycerol ( pH 7.2)
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-DBN1 antibody (Drebrin 1) (ABIN151450) Western Blot: Drebrin Antibody (M2F6) [ABIN151450] - Western blot analysis of mouse b...
Western Blotting (WB) image for anti-DBN1 antibody (Drebrin 1) (ABIN151450) Western Blot: Drebrin 1 Antibody (M2F6) [ABIN151450] - Analysis of Drebrin expression...
Product cited in: Bhat, Thirumangalakudi: "Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet." in: Journal of Alzheimer's disease : JAD, Vol. 36, Issue 4, pp. 781-9, 2013 (PubMed).

Chen, Prior, Dargusch, Roberts, Riek, Eichmann, Chiruta, Akaishi, Abe, Maher, Schubert: "A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease." in: PLoS ONE, Vol. 6, Issue 12, pp. e27865, 2011 (PubMed).

Maezawa, Nivison, Montine, Maeda, Montine: "Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 6, pp. 797-9, 2006 (PubMed).

Background publications Peitsch, Grund, Kuhn, Schnölzer, Spring, Schmelz, Franke: "Drebrin is a widespread actin-associating protein enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells." in: European journal of cell biology, Vol. 78, Issue 11, pp. 767-78, 2000 (PubMed).

Shirao: "The roles of microfilament-associated proteins, drebrins, in brain morphogenesis: a review." in: Journal of biochemistry, Vol. 117, Issue 2, pp. 231-6, 1995 (PubMed).

Kojima, Kato, Shirao, Obata: "Nucleotide sequences of two embryonic drebrins, developmentally regulated brain proteins, and developmental change in their mRNAs." in: Brain research, Vol. 464, Issue 3, pp. 207-15, 1989 (PubMed).