DBN1 antibody (Drebrin 1)

Details for Product anti-DBN1 Antibody No. ABIN151450, Supplier: Log in to see
Antigen
  • LOC733967
  • D0S117E
  • DBN1
  • drebrin 1
  • drebrin-like
  • DBN1
  • dbn1
  • LOC733967
  • LOC100224486
  • Dbn1
  • DBNL
Alternatives
anti-Human DBN1 antibody for Immunofluorescence (fixed cells)
Reactivity
Cow (Bovine), Chicken, Cat (Feline), Human, Mouse (Murine), Rabbit, Rat (Rattus)
85
38
36
7
6
3
1
1
Host
Mouse
39
38
11
1
Clonality (Clone)
Monoclonal ()
Conjugate
This DBN1 antibody is un-conjugated
6
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
66
23
22
21
20
15
13
11
9
7
2
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen Chicken Drebrin E protein.
Clone M2F6
Isotype IgG1
Purification Protein A purified
Alternative Name Drebrin 1 (DBN1 Antibody Abstract)
Background Gene Symbol: DBN1
Gene ID 1627
UniProt P18302
Pathways Maintenance of Protein Location
Application Notes Western Blot 1 μg/mL, Immunohistochemistry 10 μg/mL, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin 10 μg/mLIn Western Blot a 110 kDa band is seen due to large amounts of negative residues (predicted MW 71 kDa). This antibody has been reported in the literature to work in Immunohistochemistry (PMID: 1314351)
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS ( pH 7.2) and 50 % Glycerol
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-DBN1 antibody (Drebrin 1) (ABIN151450) Western Blot: Drebrin Antibody (M2F6) [ABIN151450] - Western blot analysis of mouse b...
Western Blotting (WB) image for anti-DBN1 antibody (Drebrin 1) (ABIN151450) Western Blot: Drebrin 1 Antibody (M2F6) [ABIN151450] - Analysis of Drebrin expression...
Product cited in: Bhat, Thirumangalakudi: "Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet." in: Journal of Alzheimer's disease : JAD, Vol. 36, Issue 4, pp. 781-9, 2013 (PubMed).

Chen, Prior, Dargusch, Roberts, Riek, Eichmann, Chiruta, Akaishi, Abe, Maher, Schubert: "A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease." in: PLoS ONE, Vol. 6, Issue 12, pp. e27865, 2011 (PubMed).

Maezawa, Nivison, Montine, Maeda, Montine: "Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 6, pp. 797-9, 2006 (PubMed).

Background publications Peitsch, Grund, Kuhn, Schnölzer, Spring, Schmelz, Franke: "Drebrin is a widespread actin-associating protein enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells." in: European journal of cell biology, Vol. 78, Issue 11, pp. 767-78, 2000 (PubMed).

Shirao: "The roles of microfilament-associated proteins, drebrins, in brain morphogenesis: a review." in: Journal of biochemistry, Vol. 117, Issue 2, pp. 231-6, 1995 (PubMed).

Kojima, Kato, Shirao, Obata: "Nucleotide sequences of two embryonic drebrins, developmentally regulated brain proteins, and developmental change in their mRNAs." in: Brain research, Vol. 464, Issue 3, pp. 207-15, 1989 (PubMed).