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Dihydropyrimidinase-Like 3 (DPYSL3) (C-Term) antibody

Details for Product No. ABIN1514914
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Antigen
Synonyms
CRMP4A, CRMP4B, dpysl3, DRP-3, MGC69487, dpysl3-b, crmp4, CRMP-4, xCRMP4, DRP-3-B, DPYSL3, CRMP4, DRP3, LCRMP, ULIP, ULIP-1, TUC4, Ulip, Ulip1, Crmp4, TUC-4b, drp-3, drp3, lcrmp, nsp1, tuc-4, tuc4, ul ... show more
CRMP4A, CRMP4B, dpysl3, DRP-3, MGC69487, dpysl3-b, crmp4, CRMP-4, xCRMP4, DRP-3-B, DPYSL3, CRMP4, DRP3, LCRMP, ULIP, ULIP-1, TUC4, Ulip, Ulip1, Crmp4, TUC-4b, drp-3, drp3, lcrmp, nsp1, tuc-4, tuc4, ulip, ulip-1 show less
Epitope
C-Term
(13), (9), (7), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(56), (20), (19), (13), (13), (1), (1), (1), (1)
Host
Rabbit
(44), (14)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
(49), (29), (19), (10), (9), (5), (4), (2), (2), (2)
Pubmed 9 references available
Quantity 100 µg
Options
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Catalog No. ABIN1514914
543.69 $
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Immunogen A 15 residue synthetic peptide derived from C-terminal domain of human collapsing-response mediator
Isotype IgG
Specificity Reacts with 65 kDa CRMP-4 from human rat and mouse.
Cross-Reactivity (Details) Reacts with 65 kDa CRMP-4 from human rat and mouse. Do not react with CRMP-1, CRMP-2, CRMP-3 or CRMP-5.
Purification Purified (protein A)
Alternative Name Collapsin response mediator protein 4 (CRMP-4)
Application Notes Optimal dilution should be determined by the end user.
The following are guidelines only: IHC: 1/500, WB: 1/2 000
Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Buffer Tris 0,1 M, glycine 0,1 M, sucrose 2 %
Storage 4 °C/-20 °C
Storage Comment Lyophilized powder stable for a minimum of 2 years at -20 °C. Store reconstituted antibodies at +4 °C. For extended periods store in aliquots at -20 °C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 24 months
Supplier Images
anti-Dihydropyrimidinase-Like 3 (DPYSL3) (C-Term) antibody anti-Dihydropyrimidinase-Like 3 (DPYSL3) (C-Term) antibody
anti-Dihydropyrimidinase-Like 3 (DPYSL3) (C-Term) antibody (2) anti-Dihydropyrimidinase-Like 3 (DPYSL3) (C-Term) antibody (Image 2)
Product cited in: Balin, Loewy, Appelt: "Analysis of transglutaminase-catalyzed isopeptide bonds in paired helical filaments and neurofibrillary tangles from Alzheimer's disease." in: Methods in enzymology, Vol. 309, pp. 172-86, 1999 (PubMed).

Honnorat, Byk, Kusters et al.: "Ulip/CRMP proteins are recognized by autoantibodies in paraneoplastic neurological syndromes." in: The European journal of neuroscience, Vol. 11, Issue 12, pp. 4226-32, 2000 (PubMed).

Ricard, Rogemond, Charrier et al.: "Isolation and expression pattern of human Unc-33-like phosphoprotein 6/collapsin response mediator protein 5 (Ulip6/CRMP5): coexistence with Ulip2/CRMP2 in Sema3a- sensitive oligodendrocytes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 18, pp. 7203-14, 2001 (PubMed).

Charrier, Reibel, Rogemond et al.: "Collapsin response mediator proteins (CRMPs): involvement in nervous system development and adult neurodegenerative disorders." in: Molecular neurobiology, Vol. 28, Issue 1, pp. 51-64, 2003 (PubMed).

Quach, Duchemin, Rogemond et al.: "Involvement of collapsin response mediator proteins in the neurite extension induced by neurotrophins in dorsal root ganglion neurons." in: Molecular and cellular neurosciences, Vol. 25, Issue 3, pp. 433-43, 2004 (PubMed).

Bretin, Reibel, Charrier et al.: "Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain." in: The Journal of comparative neurology, Vol. 486, Issue 1, pp. 1-17, 2005 (PubMed).

Veyrac, Giannetti, Charrier et al.: "Expression of collapsin response mediator proteins 1, 2 and 5 is differentially regulated in newly generated and mature neurons of the adult olfactory system." in: The European journal of neuroscience, Vol. 21, Issue 10, pp. 2635-48, 2005 (PubMed).

Duplan, Bernard, Casseron et al.: "Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 2, pp. 785-96, 2010 (PubMed).

Blasco, Bernard-Marissal, Vourch et al.: "A rare motor neuron deleterious missense mutation in the DPYSL3 (CRMP4) gene is associated with ALS." in: Human mutation, Vol. 34, Issue 7, pp. 953-60, 2013 (PubMed).

Validation Images
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