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Aurora Kinase A (AURKA) (C-Term), (AA 1-19) antibody

Details for Product No. ABIN151760
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Antigen
Synonyms
AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, AIRK1, AU019385, AW539821, Ark1, Aurora-A, Ayk1, IAK, IAK1, Stk6, ARK-1, Eg2, aik, ark1, aur-a, aura, aurka-a, aurora2, btak, stk15, stk6, s ... show more
AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, AIRK1, AU019385, AW539821, Ark1, Aurora-A, Ayk1, IAK, IAK1, Stk6, ARK-1, Eg2, aik, ark1, aur-a, aura, aurka-a, aurora2, btak, stk15, stk6, stk7, 87A7-9/2, Aur-A, AurA, CG3068, Dmel\\CG3068, aur-A, aurA, ck10, ck[10], l(3)87Ac, l(3)ck10, pEg2, wu:fb37c10, wu:fc02c02, zgc:100912, AURKA, aurka show less
Epitope
C-Term, AA 1-19
(30), (25), (13), (7), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(169), (55), (45), (27), (26), (13), (12)
Host
Rabbit
(126), (44), (12), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Microarray (MA)
(135), (74), (42), (38), (38), (26), (20), (18), (9), (5), (1), (1)
Pubmed 4 references available
Quantity 0.1 mL
Shipping to United States (Change)
Catalog No. ABIN151760
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Immunogen Synthetic peptide corresponding to amino acids 1-19 of human Aurora B with C-terminal added cysteine conjugated to KLH
Specificity Aurora B
Purification affinity purified
Alternative Name Aurora kinase
Background Chromosomal segregation during mitosis as well as meiosis is regulated by kinases andphosphatases. The Aurora kinases associate with microtubules during chromosomemovement and segregation. Aurora kinase B localizes to microtubules nearkinetochores, specifically to the specialized microtubules called K-fibers, and Aurorakinase A localizes to centrosomes. Alternate Names: anti-AIK2 antibody, anti-AIM1 antibody, anti-ARK2 antibody, anti-AURKB antibody,anti-Aurora 1 antibody, anti-Aurora kinase B antibody, anti-Aurora- and Ipl1-likemidbody-associated protein 1 antibody, anti-Aurora-related kinase 2 antibody,anti-Aurora/IPL1 related kinase 2 antibody, anti-IPL1 antibody.
Gene Symbol: AURKB
Gene ID 9212, 20877, 114592
Application Notes By Western blot, it detects a band of approximately 39 kDa. It can also be used for indirect immunofluorescence and immunoprecipitation. Immunohistochemistry was reported in scientific literature. The IF dilution given is for indirect.
Recommended dilutions: Immunocytochemistry/Immunofluorescence 1:50, Immunohistochemistry 1:10-1:2000, Immunoprecipitation 60 µg / 300 µg lysate, Microarray, Western Blot 1:1000-1:2000
Restrictions For Research Use only
Format Liquid
Concentration 12.5 mg/mL
Buffer 0.01 M PBS, pH 7.4, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
Supplier Images
anti-Aurora Kinase A (AURKA) (C-Term), (AA 1-19) antibody anti-Aurora Kinase A (AURKA) (C-Term), (AA 1-19) antibody
General Giet, Prigent: "Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases." in: Journal of cell science, Vol. 112 ( Pt 21), pp. 3591-601, 1999 (PubMed).

Hsu, Sun, Li et al.: "Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes." in: Cell, Vol. 102, Issue 3, pp. 279-91, 2000 (PubMed).

Adams, Eckley, Vagnarelli et al.: "Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells." in: Chromosoma, Vol. 110, Issue 2, pp. 65-74, 2001 (PubMed).

Lee, Frolov, Li et al.: "Targeting Aurora kinases for the treatment of prostate cancer." in: Cancer research, Vol. 66, Issue 10, pp. 4996-5002, 2006 (PubMed).

Hosts (126), (44), (12), (1)
Reactivities (169), (55), (45), (27), (26), (13), (12)
Applications (135), (74), (42), (38), (38), (26), (20), (18), (9), (5), (1), (1)
Conjugates (8), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (30), (25), (13), (7), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN151760
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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