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Details for Product No. ABIN151760

Aurora Kinase A (AURKA) antibody

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Antigen
Synonyms
AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, AIRK1, AU019385, AW539821, Ark1, Aurora-A, Ayk1, IAK, IAK1, Stk6, ARK-1, Eg2, aik, ark1, aur-a, aura, aurka-a, aurora2, btak, stk15, stk6, s ... show more
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN151760
Quantity 0.1 mL
Price
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Immunogen Synthetic peptide corresponding to amino acids 1-19 of human Aurora B.
Specificity Species Reactivity: Human, mouse, and rat. Not yet tested in other species.
Cross-Reactivity Hamster, Human, Mouse (Murine), Rat (Rattus)
Purification Purified
Alternative Name Aurora kinase
Background Chromosomal segregation during mitosis as well as meiosis is regulated by kinases andphosphatases. The Aurora kinases associate with microtubules during chromosomemovement and segregation. Aurora kinase B localizes to microtubules nearkinetochores, specifically to the specialized microtubules called K-fibers, and Aurorakinase A localizes to centrosomes. Alternate Names: anti-AIK2 antibody, anti-AIM1 antibody, anti-ARK2 antibody, anti-AURKB antibody,anti-Aurora 1 antibody, anti-Aurora kinase B antibody, anti-Aurora- and Ipl1-likemidbody-associated protein 1 antibody, anti-Aurora-related kinase 2 antibody,anti-Aurora/IPL1 related kinase 2 antibody, anti-IPL1 antibody.
Gene ID 9212, 20877, 114592
Application Notes Suggested working dilutions: immunofluorescence (indirect) 1:2,000,immunoprecipitation 60 ug / 300 ug lysate,Western Blot 1:1,000-1:2,000. Positive Controls: PC-12, NIH-3T3
Restrictions For Research Use only
Format Liquid
Buffer Preservative: Sodium Azide.
Preservative Sodium azide
Storage 4 °C
Giet, Prigent: "Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases." in: Journal of cell science, Vol. 112 ( Pt 21), pp. 3591-601, 1999 (PubMed).

Hsu, Sun, Li et al.: "Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes." in: Cell, Vol. 102, Issue 3, pp. 279-91, 2000 (PubMed).

Adams, Eckley, Vagnarelli et al.: "Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells." in: Chromosoma, Vol. 110, Issue 2, pp. 65-74, 2001 (PubMed).

Lee, Frolov, Li et al.: "Targeting Aurora kinases for the treatment of prostate cancer." in: Cancer research, Vol. 66, Issue 10, pp. 4996-5002, 2006 (PubMed).

Alternatives for antigen "Aurora Kinase A (AURKA)", type "Antibodies"
Hosts (118), (43), (14), (2)
Reactivities (166), (57), (48), (26), (24), (14), (10), (1), (1), (1)
Applications (131), (62), (46), (42), (33), (30), (20), (16), (7), (4), (4), (1)
Conjugates (8), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Epitopes (29), (15), (12), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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