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Aurora Kinase A (AURKA) antibody

Antigen

Aurora Kinase A (AURKA)
Synonyms
AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, IAK, Ark1, Ayk1, Stk6, AIRK1, AU019385, AW539821, Aurora-A, 87A7-9/2, AurA, ck10, ck[10], l(3)87Ac, l(3)ck10, DmelCG3068, CG3068, MGC124935 ... show more
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Hamster
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
4 references available
Catalog no. ABIN151760
Quantity 0.1 ml  (Variants)
Price Product not available in this region.
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anti-Aurora Kinase A (AURKA) antibody

Additional Information
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Alternative name Aurora kinase
Gene ID 9212, 20877, 114592
Immunogen Synthetic peptide corresponding to amino acids 1-19 of human Aurora B.
Cross-Reactivity Hamster, Human, Mouse (Murine), Rat (Rattus)
Description Chromosomal segregation during mitosis as well as meiosis is regulated by kinases andphosphatases. The Aurora kinases associate with microtubules during chromosomemovement and segregation. Aurora kinase B localizes to microtubules nearkinetochores, specifically to the specialized microtubules called K-fibers, and Aurorakinase A localizes to centrosomes. Alternate Names: anti-AIK2 antibody, anti-AIM1 antibody, anti-ARK2 antibody, anti-AURKB antibody,anti-Aurora 1 antibody, anti-Aurora kinase B antibody, anti-Aurora- and Ipl1-likemidbody-associated protein 1 antibody, anti-Aurora-related kinase 2 antibody,anti-Aurora/IPL1 related kinase 2 antibody, anti-IPL1 antibody.
Specificity Species Reactivity: Human, mouse, and rat. Not yet tested in other species.
Synonyms AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, IAK, Ark1, Ayk1, Stk6, AIRK1, AU019385, AW539821, Aurora-A, 87A7-9/2, AurA, ck10, ck[10], l(3)87Ac, l(3)ck10, DmelCG3068, CG3068, MGC124935, aurka, AURKA, MGC134472, aik, ark1, aura, btak, stk6, stk7, stk15, aurora2, zgc:100912

Application Details
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Application Notes Suggested working dilutions: immunofluorescence (indirect) 1:2,000,immunoprecipitation 60 ug / 300 ug lysate,Western Blot 1:1,000-1:2,000. Positive Controls: PC-12, NIH-3T3
Purification Purified
Buffer Preservative: Sodium Azide.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
Restrictions For Research Use only

Publications
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Giet, Prigent: "Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases." in: Journal of cell science, Vol. 112 ( Pt 21), pp. 3591-601, 1999 (PubMed).

Hsu, Sun, Li et al.: "Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes." in: Cell, Vol. 102, Issue 3, pp. 279-91, 2000 (PubMed).

Adams, Eckley, Vagnarelli et al.: "Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells." in: Chromosoma, Vol. 110, Issue 2, pp. 65-74, 2001 (PubMed).

Lee, Frolov, Li et al.: "Targeting Aurora kinases for the treatment of prostate cancer." in: Cancer research, Vol. 66, Issue 10, pp. 4996-5002, 2006 (PubMed).

Alternatives
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Alternatives for antigen "Aurora Kinase A (AURKA)", type "Antibodies"
Hosts Rabbit (87), Mouse (25), Goat (9), Sheep (1)
Reactivities Human (114), Mouse (Murine) (31), Rat (Rattus) (31), Cow (Bovine) (21), Horse (Equine) (18), Pig (Porcine) (18), Dog (Canine) (7), Monkey (7), Sheep (Ovine) (5), Cat (Feline) (1), Chicken (1)
Applications Western Blotting (WB) (92), ELISA (57), Immunofluorescence (IF) (43), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (27), Immunohistochemistry (IHC) (23), Immunoprecipitation (IP) (21), Flow Cytometry (FACS) (7), Immunohistochemistry (Fixed) (IHC (fx)) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Biotin (5), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes N-Term (15), pThr288 (14), C-Term (13), AA 100-150 (1), Internal Region (1), N-Term,Glu107 (1), N-Term,Ser89 (1), pSer241 (1), pThr198,pThr232 (1)