Aurora Kinase B antibody (AURKB) (C-Term)

Details for Product anti-AURKB Antibody No. ABIN151760, Supplier: Log in to see
Antigen
  • Aur B
  • AurB
  • Aurora B
  • Aurora-B
  • CG6620
  • DmAIRK2
  • DmAurB
  • DmAuroraB
  • Dmel\\CG6620
  • IAL
  • IAL1
  • Ial
  • aurB
  • aurora B
  • XAIRK2
  • aik2
  • aim-1
  • aim1
  • airk2
  • ark2
  • ipl1
  • stk12
  • stk5
  • aurkb
  • AIK2
  • AIM-1
  • AIM1
  • ARK2
  • IPL1
  • PPP1R48
  • STK12
  • STK5
  • aurkb-sv1
  • aurkb-sv2
  • AIRK2
  • AL022959
  • Aik2
  • Aim1
  • Ark2
  • STK-1
  • Stk12
  • Stk5
  • ARK-2
  • CHUNP6896
  • fa09g06
  • stka
  • wu:fa09g06
  • IKK2
  • IplI-aurora-like kinase
  • aurora kinase B
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • ial
  • aurkb
  • AURKB
  • Aurkb
  • Ikbkb
Alternatives
anti-Human Aurora Kinase B antibody for Western Blotting
Epitope
C-Term
32
32
20
20
14
14
14
14
13
7
7
6
5
4
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
295
134
105
29
29
23
22
12
7
3
2
2
2
1
1
Host
Rabbit
192
99
8
5
Clonality
Polyclonal
Conjugate
This Aurora Kinase B antibody is un-conjugated
10
10
10
9
7
6
4
4
4
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Microarray (MA), Western Blotting (WB)
240
145
124
77
69
43
30
13
11
11
3
2
2
2
1
Options
Supplier
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Supplier Product No.
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Immunogen Synthetic peptide corresponding to amino acids 1-19 of human Aurora B with C-terminal added cysteine conjugated to KLH.
Specificity Aurora B
Purification Immunogen affinity purified
Alternative Name Aurora B (AURKB Antibody Abstract)
Background Gene Symbol: AURKB
Gene ID 9212
Research Area Signaling, Kinases/Phosphatases, Cell Cycle, Cancer
Pathways TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
Application Notes Western Blot 1:1000-1:2000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:50, Immunoprecipitation 60 μg/ 300 μg lysate, Immunohistochemistry-Paraffin 1:10-1:500, MicroarrayBy Western blot, it detects a band of approximately 39 kDa.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 12.5 mg/mL
Buffer 10 mM PBS ( pH 7.4)
Buffer contains: 15 mM Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Supplier Images
Immunohistochemistry (IHC) image for anti-Aurora Kinase B (AURKB) (C-Term) antibody (ABIN151760) anti-Aurora Kinase B (AURKB) (C-Term) antibody
Immunofluorescence (IF) image for anti-Aurora Kinase B (AURKB) (C-Term) antibody (ABIN151760) Immunocytochemistry/Immunofluorescence: Aurora B Antibody [ABIN151760] - IF analysis ...
Immunofluorescence (IF) image for anti-Aurora Kinase B (AURKB) (C-Term) antibody (ABIN151760) Immunofluorescence: Aurora B Antibody [ABIN151760] - 293T cells stained with Aurora B...
Immunofluorescence (IF) image for anti-Aurora Kinase B (AURKB) (C-Term) antibody (ABIN151760) Immunocytochemistry/Immunofluorescence: Aurora B Antibody [ABIN151760] - RPE1 cells s...
Product cited in: Sijare, Geißler, Fichter, Hergeth, Bogatyreva, Hauschke, Schneider, Werner, Lassmann: "Aurora B expression and histone variant H1.4S27 phosphorylation are no longer coordinated during metaphase in aneuploid colorectal carcinomas." in: Virchows Archiv : an international journal of pathology, Vol. 466, Issue 5, pp. 503-15, 2015 (PubMed). Further details: Immunocytochemistry,Immunofluorescence

Kleyman, Kabeche, Compton: "STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments." in: Journal of cell science, Vol. 127, Issue Pt 19, pp. 4225-33, 2014 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Kabeche, Compton: "Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation." in: Nature, Vol. 502, Issue 7469, pp. 110-3, 2013 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Kabeche, Compton: "Checkpoint-independent stabilization of kinetochore-microtubule attachments by Mad2 in human cells." in: Current biology : CB, Vol. 22, Issue 7, pp. 638-44, 2012 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Beussel, Hasenburg, Bogatyreva, Hauschke, Werner, Lassmann: "Aurora-B protein expression is linked to initial response to taxane-based first-line chemotherapy in stage III ovarian carcinoma." in: Journal of clinical pathology, Vol. 65, Issue 1, pp. 29-35, 2011 (PubMed). (Sample species: Human). Further details: Immunohistochemistry

Bufo, Sanguedolce, Tortorella, Cormio, Carrieri, Pannone: "Expression of mitotic kinases phospho-aurora A and aurora B correlates with clinical and pathological parameters in bladder neoplasms." in: Histology and histopathology, Vol. 25, Issue 11, pp. 1371-7, 2010 (PubMed).

Lee, Frolov, Li, Ayala, Greenberg: "Targeting Aurora kinases for the treatment of prostate cancer." in: Cancer research, Vol. 66, Issue 10, pp. 4996-5002, 2006 (PubMed).

Hsu, Sun, Li, Reuben, Tatchell, Bishop, Grushcow, Brame, Caldwell, Hunt, Lin, Smith, Allis: "Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes." in: Cell, Vol. 102, Issue 3, pp. 279-91, 2000 (PubMed).

Background publications Adams, Eckley, Vagnarelli, Wheatley, Gerloff, Mackay, Svingen, Kaufmann, Earnshaw: "Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells." in: Chromosoma, Vol. 110, Issue 2, pp. 65-74, 2001 (PubMed).

Giet, Prigent: "Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases." in: Journal of cell science, Vol. 112 ( Pt 21), pp. 3591-601, 1999 (PubMed).

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