Stromal Antigen 2 (STAG2) antibody

Details for Product No. ABIN151766
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms SA-2, SA2, SCC3B, bA517O1.1, RGD1562042, 9230105L23Rik, B230112I07Rik, SAP2, XSA2, sa2, sa2-a, STAG2, stag2
Reactivity
Human
(30), (19), (15), (11), (3), (1), (1)
Host
Goat
(15), (12), (5), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunofluorescence (IF), Western Blotting (WB)
(23), (14), (9), (7), (6), (3), (2)
Pubmed 2 references available
Catalog no. ABIN151766
Quantity 0.1 mL
Price
Contact our Customer Service for availability and price in your country.
Shipping to United States (Change)
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A 31 amino acid synthetic peptide, which represented a portion of human StromalAntigen 2 encoded within exon 31 (LocusLink ID 10735).
Specificity ABIN151766 is specific for human SA2 protein. Species Reactivity: ABIN151766 reacts with human and Xenopus. Other species have not been tested.
Cross-Reactivity Human, Xenopus laevis
Purification Aff - Purified
Alternative Name STAG2 / Stromal gen 2
Background SA2 is a component of the cohesin complex, which is required for the cohesion of sisterchromatids after DNA replication. The cohesin complex apparently forms a largeproteinaceous ring within which, sister chromatids can be trapped. At anaphase, thecomplex is cleaved and dissociates from chromatin, allowing sister chromatids tosegregate. The cohesin complex may also play a role in spindle pole assembly duringmitosis.The subunit interacts directly with RAD21 in cohesin complex. Cohesin complexes arecomposed of a heterodimer between a SMC1 protein (SMC1L1 or SMC1L2) and SMC3,which are attached via their hinge domain, and RAD21 links them at their heads, andone STAG protein (STAG1, STAG2 or STAG3). In cohesin complexes, STAG2 ismutually exclusive with STAG1 and STAG3. Alternate Names: anti-SA-2 antibody, anti-STAG2 antibody, anti-Stromal Antigen 2 antibody, anti-CohesinSubunit SA2 antibody, anti-SCC3 homolog 2 antibody.
Application Notes ABIN151766 may be used for Western Blot where a band at ~140 kD is seen onSDS-PAGE. It may also be used for immunocytochemistry.Suggested working dilutions: *Western Blot 1:1,000-1:10,000 (ECL)Immunocytochemistry 1:500-1:2,000, Immunoprecipitation Not Done
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/ml
Buffer 0.1 ml of affinity purified goat sera in a Tris-citrate/phosphate (pH 7-8) buffer with 0.1%Sodium Azide. Protein concentration is 1.0 mg/ml.
Preservative Sodium azide
Storage -20 °C
Supplier Images
anti-Stromal Antigen 2 (STAG2) antibody anti-Stromal Antigen 2 (STAG2) antibody
General Yalcin, Zhang, Luciano et al.: "Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells." in: The Journal of biological chemistry, Vol. 283, Issue 37, pp. 25692-705, 2008 (PubMed).

Zhang, Kuznetsov, Sharan et al.: "A handcuff model for the cohesin complex." in: The Journal of cell biology, Vol. 183, Issue 6, pp. 1019-31, 2008 (PubMed).

Hosts (15), (12), (5), (1)
Reactivities (30), (19), (15), (11), (3), (1), (1)
Applications (23), (14), (9), (7), (6), (3), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (2), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
back to top