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Details for Product No. ABIN151815

BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1) antibody

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Antigen
Synonyms BACH1, FANCJ, OF, 3110009N10Rik, 8030460J03Rik, Bach1, FACJ, Fancj, MGC68622, BRIP1, fancj, si:ch211-158l18.1
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN151815
Quantity 0.1 mL
Price
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Immunogen Fusion protein 647-1043 of human Brip1.
Clone GO11-3E6
Isotype IgG1
Specificity This antibody is specific for Brip1. Species Reactivity: ABIN151815 recognizes human Brip1. Localization: Nuclear.
Cross-Reactivity Human
Purification Ascites
Alternative Name BRIP1 / FANCJ
Background BRIP1 (also called BACH1) is a helicase that interacts with the BRCT domain of BRCA1and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 has recentlybeen found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJhas a function in the Fanconi anemia pathway that is independent of BRCA1 anddownstream of FANCD2 activation. (1-4). Alternate Names: anti-FANCJ protein antibody, anti-BACH 1 antibody, anti-BACH1 BRIP1 antibody,anti-BRIP 1 antibody, anti-BRAC 1 Associated C Terminal Helicase 1 antibody,anti-BRCA 1 Interacting Protein 1 antibody, anti-Fanconi anemia group J protein.
Gene ID 83990
UniProt Q9BX63
Application Notes Positive Controls: HeLa whole and nuclear extracts, Raji whole cell extracts.
Restrictions For Research Use only
Format Liquid
Concentration 16.3 mg/ml
Buffer Preservative: Sodium Azide.
Preservative Sodium azide
Storage 4 °C
Ohira, Seki, Nagase et al.: "Characterization of a human homolog (BACH1) of the mouse Bach1 gene encoding a BTB-basic leucine zipper transcription factor and its mapping to chromosome 21q22.1." in: Genomics, Vol. 47, Issue 2, pp. 300-6, 1998 (PubMed).

Cantor, Bell, Ganesan et al.: "BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function." in: Cell, Vol. 105, Issue 1, pp. 149-60, 2001 (PubMed).

Alternatives for antigen "BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1)", type "Antibodies"
Hosts (43), (17), (1)
Reactivities (58), (28), (24), (12), (12), (12), (12), (12)
Applications (39), (20), (13), (12), (9), (6), (2), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (12), (6), (4), (3), (2), (2), (2), (1), (1), (1)
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