CREB1 antibody (CAMP Responsive Element Binding Protein 1) (pSer121)

Details for Product anti-CREB1 Antibody No. ABIN151873, Supplier: Log in to see
Antigen
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein 1a
  • cyclic AMP response element binding protein
  • CREB1
  • creb1
  • Creb1
  • LOC100351999
  • creb1a
  • CREB
Alternatives
anti-Mouse (Murine) CREB1 antibody for Chromatin Immunoprecipitation
Epitope
pSer121
131
37
37
36
20
18
17
16
15
15
8
7
7
6
6
5
5
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
537
328
298
41
38
36
30
27
26
26
19
17
15
12
7
7
7
2
1
1
1
1
Host
Rabbit
437
101
11
1
Clonality
Polyclonal
Conjugate
This CREB1 antibody is un-conjugated
18
15
15
7
7
6
6
6
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
Application
Immunoprecipitation (IP), Western Blotting (WB)
431
215
191
99
92
44
43
42
30
11
11
10
4
3
3
2
2
1
1
1
Options
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Immunogen A phospho-peptide spanning the Ser121 phosphorylation site of human CREB [UniProt# P16220]
Purification Immunogen affinity purified
Alternative Name CREB (CREB1 Antibody Abstract)
Background Gene Symbol: CREB1
Gene ID 1385
UniProt P16220
Research Area Immunology, Innate Immunity, Transcription Factors
Pathways TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
Application Notes Western Blot 1:500, Immunoprecipitation 0.5 μgThis CREB [p Ser121] antibody is useful for Immunoprecipitation and Western blot.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.3 mg/mL
Buffer Tris and 50 % Glycerol
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-CREB1 antibody (CAMP Responsive Element Binding Protein 1) (pSer121) (ABIN151873) Detection of phospho-CREB in human HEK 293T cells. Top panel: probed with ABIN151873....
Product cited in: Byrd, Stewart, Smith, Eaton, Taylor, Guy, Eringyte, Fooks, Last, Horsley, Oliver, Janic, Dokmanovic, Stankovic, Taylor: "A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development." in: PLoS genetics, Vol. 12, Issue 3, pp. e1005945, 2016 (PubMed).

Steven, Leisz, Sychra, Hiebl, Wickenhauser, Mougiakakos, Kiessling, Denkert, Seliger: "Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization." in: Oncotarget, Vol. 7, Issue 32, pp. 52061-52084, 2016 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Human).

Byrd, Srinivasan, Last, Smith, Biggs, Carney, Exley, Abson, Stewart, Izatt, Taylor: "Severe reaction to radiotherapy for breast cancer as the presenting feature of ataxia telangiectasia." in: British journal of cancer, Vol. 106, Issue 2, pp. 262-8, 2012 (PubMed).

Shanware, Trinh, Williams, Tibbetts: "Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage." in: The Journal of biological chemistry, Vol. 282, Issue 9, pp. 6283-91, 2007 (PubMed).

Shi, Dodson, Mukhopadhyay, Shanware, Trinh, Tibbetts: "Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies." in: The Journal of biological chemistry, Vol. 282, Issue 12, pp. 9236-43, 2007 (PubMed).

Dodson, Tibbetts: "DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM." in: The Journal of biological chemistry, Vol. 281, Issue 3, pp. 1692-7, 2006 (PubMed). (Sample species: Human). Further details: Western Blotting

Shi, Dodson, Shaikh, Rundell, Tibbetts: "Ataxia-telangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo." in: The Journal of biological chemistry, Vol. 280, Issue 48, pp. 40195-200, 2005 (PubMed).

Shi, Venkataraman, Dodson, Mabb, LeBlanc, Tibbetts: "Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 16, pp. 5898-903, 2004 (PubMed).