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BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1) antibody

Antigen

BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1)
Synonyms OF, BACH1, FANCJ, FLJ90232, MGC126521, MGC126523, Bach1, 3110009N10Rik, 8030460J03Rik, MGC68622, BRIP1, fancj, si:ch211-158l18.1
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunoprecipitation (IP), Western Blotting (WB)
1 reference available
Catalog no. ABIN151876
Quantity 0.1 ml  (Variants)
Price Product not available in this region.
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anti-BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1) antibody

anti-BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1) antibody (2)

Additional Information
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Alternative name BRIP1 / FANCJ
Gene ID 83990
UniProt Q9BX63
Immunogen A synthetic peptide within the extreme C-terminus of the human FANCJ/BACH1/Brip1protein sequence.
Cross-Reactivity Human
Format Serum
Description BRIP1 (also called BACH1 /FANCJ) is a helicase that interacts with the BRCT domainof BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 hasrecently been found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent ofBRCA1 and downstream of FANCD2 activation. (1-4). Alternate Names: anti-FANCJ protein antibody, anti-BACH 1 antibody, anti-BACH1 antibody, anti-BRIP1antibody, anti-BRIP 1 antibody, anti-BRAC 1 Associated C Terminal Helicase 1antibody, anti-BRCA 1 Interacting Protein 1 antibody, anti- Fanconi anemia group Jprotein.
Specificity This antibody is specific for BACH1/Brip1/FANCJ. Species Reactivity: ABIN151876 recognizes human Brip1 / FANCJ. Localization: Nuclear.

Application Details
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Application Notes Suggested working dilutions: Western Blot 1:500. Positive Controls: HeLa whole cell extract [NB 800-PC1], and Raji, 293, MCF7 and SKOV3 whole cellextracts.
Purification Serum
Buffer Preservative: 0.01% sodium azide.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
Restrictions For Research Use only

Publications
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Cantor, Bell, Ganesan et al.: "BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function." in: Cell, Vol. 105, Issue 1, pp. 149-60, 2001 (PubMed).

Alternatives
Application Details Publications Images Variants back to top

Alternatives for antigen "BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1)", type "Antibodies"
Hosts Rabbit (35), Mouse (8), Chicken (1)
Reactivities Human (44), Mouse (Murine) (25), Rat (Rattus) (24), Chicken (19), Cow (Bovine) (19), Dog (Canine) (19), Horse (Equine) (19), Pig (Porcine) (19)
Applications Immunofluorescence (IF) (22), Western Blotting (WB) (20), ELISA (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (3), Dot Blot (Dot) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes C-Term (4), pSer990 (4), AA 1233-1249 (1), AA 92-104 (1), N-Term (1), pThr401 (1)