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Details for Product No. ABIN151876

BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1) antibody

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Antigen
Synonyms BACH1, FANCJ, OF, 3110009N10Rik, 8030460J03Rik, Bach1, FACJ, Fancj, MGC68622, BRIP1, fancj, si:ch211-158l18.1
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN151876
Quantity 0.1 mL
Price
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Immunogen A synthetic peptide within the extreme C-terminus of the human FANCJ/BACH1/Brip1protein sequence.
Specificity This antibody is specific for BACH1/Brip1/FANCJ. Species Reactivity: ABIN151876 recognizes human Brip1 / FANCJ. Localization: Nuclear.
Cross-Reactivity Human
Purification Serum
Alternative Name BRIP1 / FANCJ
Background BRIP1 (also called BACH1 /FANCJ) is a helicase that interacts with the BRCT domainof BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 hasrecently been found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent ofBRCA1 and downstream of FANCD2 activation. (1-4). Alternate Names: anti-FANCJ protein antibody, anti-BACH 1 antibody, anti-BACH1 antibody, anti-BRIP1antibody, anti-BRIP 1 antibody, anti-BRAC 1 Associated C Terminal Helicase 1antibody, anti-BRCA 1 Interacting Protein 1 antibody, anti- Fanconi anemia group Jprotein.
Gene ID 83990
UniProt Q9BX63
Application Notes Suggested working dilutions: Western Blot 1:500. Positive Controls: HeLa whole cell extract [NB 800-PC1], and Raji, 293, MCF7 and SKOV3 whole cellextracts.
Restrictions For Research Use only
Format Liquid
Buffer Preservative: 0.01% sodium azide.
Preservative Sodium azide
Storage 4 °C
Cantor, Bell, Ganesan et al.: "BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function." in: Cell, Vol. 105, Issue 1, pp. 149-60, 2001 (PubMed).

Alternatives for antigen "BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1)", type "Antibodies"
Hosts (42), (18), (1)
Reactivities (58), (28), (24), (12), (12), (12), (12), (12)
Applications (39), (20), (13), (11), (8), (6), (2), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (12), (6), (4), (3), (2), (2), (2), (1), (1), (1)
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