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Der1-Like Domain Family, Member 1 (DERL1) antibody

Antigen

Der1-Like Domain Family, Member 1 (DERL1)
Synonyms
AI195141, AW551338, Derlin-1, 1110021N07Rik, DER1, DER-1, MGC3067, PRO2577, FLJ13784, FLJ42092, RGD1311835, MGC137834, DERL1, DERLIN-1, F17A13.150, F17A13_150, DKFZp468A145, zgc:55637, wu:fb09d07, wu: ... show more
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Cow (Bovine)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
1 reference available
Catalog no. ABIN151899
Quantity 0.1 ml  (1 mg/ml)  (Variants)
Price Product not available in this region.
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anti-Der1-Like Domain Family, Member 1 (DERL1) antibody

anti-Der1-Like Domain Family, Member 1 (DERL1) antibody (2)

Additional Information
Application Details Publications Images Alternatives Variants back to top

Alternative name Derlin-1
Gene ID 79139
UniProt Q9BUN8
Immunogen A synthetic peptide made to the C-terminal region of the human Derlin-1 proteinsequence (between residues 200-251).
Cross-Reactivity Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
Description Derlin-1 is a channel-like protein, found in the ER membrane, responsible for degradingand funneling misfolded proteins and other cellular debris into the appropriatedegradative pathways within the cell. Alternate Names: anti-Degradation in endoplasmic reticulum protein 1 antibody, anti-Der1-like protein 1antibody, anti-DERtrin-1 antibody, anti-DERL1 antibody.
Specificity This antibody is specific for Derlin-1. Species Reactivity: This antibody reacts with human and canine Derlin-1. No other specie has been tested. The immunogen used for this antibody production has 100% homology with human,Xenopus, bovine, and mouse protein. Localization: Subcellular localization in the endoplasmic reticulum.
Synonyms AI195141, AW551338, Derlin-1, 1110021N07Rik, DER1, DER-1, MGC3067, PRO2577, FLJ13784, FLJ42092, RGD1311835, MGC137834, DERL1, DERLIN-1, F17A13.150, F17A13_150, DKFZp468A145, zgc:55637, wu:fb09d07, wu:fb94d05, wu:fj92g12, MGC84200, derl1

Application Details
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Application Notes Suggested working dilutions: immunohistochemistry 5-10 ug/ml,Western Blot 1:1,000-1:5,000 (ECL). Positive Controls: KRM (canine microsome) lysates. (BD offers commercial liver microsomes)
Concentration 1 mg/ml
Purification Purified
Buffer Preservative: 0.1% sodium azide.
Storage Store at 4C. Do not freeze.
Restrictions For Research Use only

Publications
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Huttunen, Guuenette, Peach et al.: "HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation." in: The Journal of biological chemistry, Vol. 282, Issue 38, pp. 28285-95, 2007 (PubMed).

Alternatives
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Alternatives for antigen "Der1-Like Domain Family, Member 1 (DERL1)", type "Antibodies"
Hosts Rabbit (30)
Reactivities Human (30), Mouse (Murine) (22), Rat (Rattus) (20), Dog (Canine) (2)
Applications Immunofluorescence (IF) (15), Western Blotting (WB) (11), ELISA (8), Immunohistochemistry (IHC) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)
Epitopes C-Term (4), N-Term (2)