Product cited in:
Soares, Battistella, Rocca, Matuo, Henriques, Larsen, Escargueil: "Ataxia telangiectasia mutated- and Rad3-related kinase drives both the early and the late DNA-damage response to the monofunctional antitumour alkylator S23906." in: The Biochemical journal, Vol. 437, Issue 1, pp. 63-73, 2011 (PubMed).
(Sample species: Human). Further details: Western Blotting
Helmink, Bredemeyer, Lee, Huang, Sharma, Walker, Bednarski, Lee, Pandita, Bassing, Sleckman: "MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks." in: The Journal of experimental medicine, Vol. 206, Issue 3, pp. 669-79, 2009 (PubMed).
Zheng, Kanagaraj, Mihaljevic, Schwendener, Sartori, Gerrits, Shevelev, Janscak: "MRE11 complex links RECQ5 helicase to sites of DNA damage." in: Nucleic acids research, Vol. 37, Issue 8, pp. 2645-57, 2009 (PubMed).
Ottini, Falchetti, Saieva, De Marco, Masala, Zanna, Paglierani, Giannini, Gulino, Nesi, Mariani Costantini, Palli: "MRE11 expression is impaired in gastric cancer with microsatellite instability." in: Carcinogenesis, Vol. 25, Issue 12, pp. 2337-43, 2004 (PubMed).
Giannini, Rinaldi, Ristori, Ambrosini, Cerignoli, Viel, Bidoli, Berni, DAmati, Scambia, Frati, Screpanti, Gulino: "Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability." in: Oncogene, Vol. 23, Issue 15, pp. 2640-7, 2004 (PubMed).
Celeste, Fernandez-Capetillo, Kruhlak, Pilch, Staudt, Lee, Bonner, Bonner, Nussenzweig: "Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks." in: Nature cell biology, Vol. 5, Issue 7, pp. 675-9, 2003 (PubMed).
Xu, Stern: "NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways." in: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 8795-803, 2003 (PubMed).
Lukas, Falck, Bartkova, Bartek, Lukas: "Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage." in: Nature cell biology, Vol. 5, Issue 3, pp. 255-60, 2003 (PubMed).
Stewart, Wang, Bignell, Taylor, Elledge: "MDC1 is a mediator of the mammalian DNA damage checkpoint." in: Nature, Vol. 421, Issue 6926, pp. 961-6, 2003 (PubMed).
Lee, Xu, Lee, Ahn, Song, Lee, Canman, Lee, Kastan, Lim: "Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage." in: Molecular cancer research : MCR, Vol. 1, Issue 9, pp. 674-81, 2003 (PubMed).
Xu, Stern: "NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 13, pp. 1842-8, 2003 (PubMed).
Uziel, Lerenthal, Moyal, Andegeko, Mittelman, Shiloh: "Requirement of the MRN complex for ATM activation by DNA damage." in: The EMBO journal, Vol. 22, Issue 20, pp. 5612-21, 2003 (PubMed).
Limoli, Giedzinski, Bonner, Cleaver: "UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 1, pp. 233-8, 2002 (PubMed).
Stracker, Carson, Weitzman: "Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex." in: Nature, Vol. 418, Issue 6895, pp. 348-52, 2002 (PubMed).
Nakanishi, Taniguchi, Ranganathan, New, Moreau, Stotsky, Mathew, Kastan, Weaver, DAndrea: "Interaction of FANCD2 and NBS1 in the DNA damage response." in: Nature cell biology, Vol. 4, Issue 12, pp. 913-20, 2002 (PubMed).
Harfst, Cooper, Neubauer, Distel, Grawunder: "Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome." in: Molecular immunology, Vol. 37, Issue 15, pp. 915-29, 2001 (PubMed).
Further details: Western Blotting
Lombard, Guarente: "Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres." in: Cancer research, Vol. 60, Issue 9, pp. 2331-4, 2000 (PubMed).
Wang, Cortez, Yazdi, Neff, Elledge, Qin: "BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures." in: Genes & development, Vol. 14, Issue 8, pp. 927-39, 2000 (PubMed).
Gatei, Young, Cerosaletti, Desai-Mehta, Spring, Kozlov, Lavin, Gatti, Concannon, Khanna: "ATM-dependent phosphorylation of nibrin in response to radiation exposure." in: Nature genetics, Vol. 25, Issue 1, pp. 115-9, 2000 (PubMed).