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Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) (AA 1-140) antibody

Details for Product No. ABIN151923
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Antigen
Synonyms CDC2, CRCS10, POLD, 125kDa, 5949, CAA61369, CG5949, DNA Pol Delta, Dm Poldelta, Dmel\\CG5949, Poldelta, dnapol delta, l(3)72Ac, Pol delta, POLD3, cdc2, pold
Epitope
AA 1-140
(4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(35), (12), (12)
Host
Mouse
(20), (13), (2)
Clonality (Clone)
Monoclonal ()
Application
Western Blotting (WB)
(34), (9), (4), (4), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
Quantity 0.1 mg
Shipping to United States (Change)
Catalog No. ABIN151923
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Immunogen Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.
Clone 607
Isotype IgG
Specificity DNA Polymerase delta (607)
Cross-Reactivity (Details) Not yet tested in other species.
Purification Protein G purified
Alternative Name POLD1
Background DNA polymerase d (delta) functions in DNA replication and DNA repair. It alsopossesses 3', to 5', exonuclease activity. In leading strand synthesis itrequires the processivity factor, PCNA. It is also possibly involved in the completion ofDNA synthesis during Okazaki fragment elongation following the initiation of synthesisby the DNA polymerase a/primase complex.
Gene Symbol: POLD1
Gene ID 5424
Application Notes WB: Use at a dilution of 1/1000. Detects a band of approximately 130 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.
Recommended dilutions: Western Blot 1:1000
Restrictions For Research Use only
Buffer PBS
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
Supplier Images
anti-Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1) (AA 1-140) antibody Detection of human DNA polymerase delta by using anti-pol delta monoclonal antibody [607] (ABIN151923) in HeLa whole cell extract.
General Juonsson, Huebscher: "Proliferating cell nuclear antigen: more than a clamp for DNA polymerases." in: BioEssays : news and reviews in molecular, cellular and developmental biology, Vol. 19, Issue 11, pp. 967-75, 1998 (PubMed).

Liu, Mo, Rodriguez-Belmonte et al.: "Identification of a fourth subunit of mammalian DNA polymerase delta." in: The Journal of biological chemistry, Vol. 275, Issue 25, pp. 18739-44, 2000 (PubMed).

Kundu, Balusu, Jaiswal et al.: "Adenomatous polyposis coli-mediated hypersensitivity of mouse embryonic fibroblast cell lines to methylmethane sulfonate treatment: implication of base excision repair pathways." in: Carcinogenesis, Vol. 28, Issue 10, pp. 2089-95, 2007 (PubMed).

Hosts (20), (13), (2)
Reactivities (35), (12), (12)
Applications (34), (9), (4), (4), (2), (2), (1), (1), (1), (1)
Epitopes (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN151923
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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