Xeroderma Pigmentosum, Complementation Group C (XPC) antibody

Details for Product No. ABIN151924
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Antigen
Synonyms RAD4, XP3, XPCC
Reactivity
Human
(49), (13), (13), (12), (12), (12), (12)
Host
Mouse
(45), (5)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(36), (19), (10), (10), (9), (6), (4), (3), (3), (2), (1), (1)
Pubmed 3 references available
Quantity 0.1 mg
Shipping to United States (Change)
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Catalog No. ABIN151924
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Immunogen Recombinant XPC purified from E. coli
Clone 3-26
Isotype IgG
Cross-Reactivity (Details) Mouse reactivity reported in scientific literature (PMID: 17229834).
Purification Protein G purified
Alternative Name XPC / XPCC
Background Human XPC (Xeroderma pigmentosum group C) is a member of a family of proteins thathas been shown to be involved in the repair of DNA via the nucleotide excision repair(NER) pathway. Specifically, XPC is believed to be a part of a heteromeric proteincomplex that is involved in the recognition of the DNA lesions during global genomicrepair but not transcription-coupled repair. Alternate Names: anti-DNA repair protein complementing XPC cells antibody, anti-p125 antibody,anti-Xeroderma pigmentosum group C complementing protein antibody, anti-Xerodermapigmentosum group III antibody, anti-XP group C antibody, anti-XP3 antibody, anti-XPCgene antibody, anti-XPCC antibody.
Gene Symbol: XPC
Gene ID 7508
Application Notes By Western blot, a band is detected at approximately 113 kDa.
Recommended dilutions: Immunocytochemistry/Immunofluorescence 1:100-1:200, Immunohistochemistry 1:10-1:2000, Immunohistochemistry-Paraffin 1:100, Western Blot 1:1000
Restrictions For Research Use only
Buffer PBS [pH 7.2]
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
Supplier Images
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody Western blot analysis of human XPC protein using anti-XPC (3.26) monoclonal antibody (ABIN151924) in Raji whole cell extract. Lane 1: 1:1,000 dilution. Lane 2: 1:500 dilution.
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (2) anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (Image 2)
anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (3) anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (Image 3)
General Aboussekhra, Biggerstaff, Shivji et al.: "Mammalian DNA nucleotide excision repair reconstituted with purified protein components." in: Cell, Vol. 80, Issue 6, pp. 859-68, 1995 (PubMed).

de Laat, Jaspers, Hoeijmakers: "Molecular mechanism of nucleotide excision repair." in: Genes & development, Vol. 13, Issue 7, pp. 768-85, 1999 (PubMed).

Lovejoy, Lock, Yenamandra et al.: "DDB1 maintains genome integrity through regulation of Cdt1." in: Molecular and cellular biology, Vol. 26, Issue 21, pp. 7977-90, 2006 (PubMed).

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