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Details for Product No. ABIN151924

Xeroderma Pigmentosum, Complementation Group C (XPC) antibody

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Synonyms XP3, RAD4, XPCC
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN151924
Quantity 0.1 mg
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Immunogen Recombinant full length human XPC protein expressed in E. coli.
Clone 3-26
Isotype IgG
Specificity Species Reactivity: Cross-reacts with Human. Not yet tested in other species. Localization: Nuclear.
Purification Purified
Alternative Name XPC / XPCC
Background Human XPC (Xeroderma pigmentosum group C) is a member of a family of proteins thathas been shown to be involved in the repair of DNA via the nucleotide excision repair(NER) pathway. Specifically, XPC is believed to be a part of a heteromeric proteincomplex that is involved in the recognition of the DNA lesions during global genomicrepair but not transcription-coupled repair. Alternate Names: anti-DNA repair protein complementing XPC cells antibody, anti-p125 antibody,anti-Xeroderma pigmentosum group C complementing protein antibody, anti-Xerodermapigmentosum group III antibody, anti-XP group C antibody, anti-XP3 antibody, anti-XPCgene antibody, anti-XPCC antibody.
Gene ID 7508
Application Notes Suggested working dilutions: Western Blot 1/1000,Immunohistochemistry-Paraffin 1:100**. Positive Controls: Raji whole cell lysate
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS [pH7.2]. Preservative: No preservative.
Storage -20 °C
Aboussekhra, Biggerstaff, Shivji et al.: "Mammalian DNA nucleotide excision repair reconstituted with purified protein components." in: Cell, Vol. 80, Issue 6, pp. 859-68, 1995 (PubMed).

de Laat, Jaspers, Hoeijmakers: "Molecular mechanism of nucleotide excision repair." in: Genes & development, Vol. 13, Issue 7, pp. 768-85, 1999 (PubMed).

Lovejoy, Lock, Yenamandra et al.: "DDB1 maintains genome integrity through regulation of Cdt1." in: Molecular and cellular biology, Vol. 26, Issue 21, pp. 7977-90, 2006 (PubMed).

Alternatives for antigen "Xeroderma Pigmentosum, Complementation Group C (XPC)", type "Antibodies"
Hosts (33), (6)
Reactivities (41), (13), (12), (12), (12), (12), (12)
Applications (30), (15), (10), (9), (6), (4), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (3), (3), (2), (1), (1)