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Xeroderma Pigmentosum, Complementation Group C (XPC) antibody

Antigen

Xeroderma Pigmentosum, Complementation Group C (XPC)
Synonyms XP3, RAD4, XPCC
Clonality Monoclonal (3-26)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
3 references available
Catalog no. ABIN151924
Quantity 0.1 mg  (1 mg/ml)
Price Product not available in this region.
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anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody

anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (2)

anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (3)

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name XPC / XPCC
Gene ID 7508
Immunogen Recombinant full length human XPC protein expressed in E. coli.
Isotype IgG
Clone 3-26
Description Human XPC (Xeroderma pigmentosum group C) is a member of a family of proteins thathas been shown to be involved in the repair of DNA via the nucleotide excision repair(NER) pathway. Specifically, XPC is believed to be a part of a heteromeric proteincomplex that is involved in the recognition of the DNA lesions during global genomicrepair but not transcription-coupled repair. Alternate Names: anti-DNA repair protein complementing XPC cells antibody, anti-p125 antibody,anti-Xeroderma pigmentosum group C complementing protein antibody, anti-Xerodermapigmentosum group III antibody, anti-XP group C antibody, anti-XP3 antibody, anti-XPCgene antibody, anti-XPCC antibody.
Specificity Species Reactivity: Cross-reacts with Human. Not yet tested in other species. Localization: Nuclear.

Application Details
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Application Notes Suggested working dilutions: Western Blot 1/1000,Immunohistochemistry-Paraffin 1:100**. Positive Controls: Raji whole cell lysate
Concentration 1 mg/ml
Buffer PBS [pH7.2]. Preservative: No preservative.
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Restrictions For Research Use only

Publications
Application Details Images Alternatives back to top

Aboussekhra, Biggerstaff, Shivji et al.: "Mammalian DNA nucleotide excision repair reconstituted with purified protein components." in: Cell, Vol. 80, Issue 6, pp. 859-68, 1995 (PubMed).

de Laat, Jaspers, Hoeijmakers: "Molecular mechanism of nucleotide excision repair." in: Genes & development, Vol. 13, Issue 7, pp. 768-85, 1999 (PubMed).

Lovejoy, Lock, Yenamandra et al.: "DDB1 maintains genome integrity through regulation of Cdt1." in: Molecular and cellular biology, Vol. 26, Issue 21, pp. 7977-90, 2006 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Xeroderma Pigmentosum, Complementation Group C (XPC)", type "Antibodies"
Hosts Rabbit (26), Mouse (2)
Reactivities Human (30), Mouse (Murine) (19), Cow (Bovine) (18), Dog (Canine) (18), Guinea Pig (18), Horse (Equine) (18), Pig (Porcine) (18), Rat (Rattus) (18)
Applications Immunofluorescence (IF) (15), Western Blotting (WB) (13), ELISA (6), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (3), Dot Blot (DB) (2), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes AA 825-875 (1), AA 890-940 (1), C-Term (1), N-Term (1)