Receptors for VEGF, VEGFB and PGF have a tyrosine-protein kinase activity. TheVEGF-kinase ligand/receptor signaling system plays a key role in vascular developmentand regulation of vascular permeability. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, arethought to be important for the development of embryonic vasculature. It has beenshown that an alternately spliced form of FLT1 produces a soluble protein, termedsFLT1, which binds vascular endothelial growth factor with high affinity, playing aninhibitory role in angiogenesis. Alternate Names: anti-VEGFR1 antibody, anti-VEGFR 1 antibody, anti-Vascular permeability factorreceptor antibody, anti-Tyrosine-protein kinase receptor FLT antibody, anti-Flt-1antibody, anti-Tyrosine-protein kinase FRT antibody, anti-Fms-like tyrosine kinase 1antibody, anti-Embryonic receptor kinase 2 antibody, anti-VEGFR2 antibody,anti-VEGFR 2 antibody, anti-Protein-tyrosine kinase receptor flk-1 antibody, anti-Fetalliver kinase 1 antibody, anti-Kinase NYK antibody, anti-FLK1 antibody, anti-KDRantibody, anti-Kinase insert domain receptor antibody, anti-KRD1 antibody, anti-Ly73antibody, anti-Protein tyrosine kinase receptor FLK1 antibody, anti-Vascular endothelialgrowth factor receptor 2 antibody.
Gene Symbol: FLT1