C-C Chemokine Receptor Type 5 (CCR5) antibody

Details for Product No. ABIN151963
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Antigen
Synonyms GPCR, CC-CKR-5, CCR-5, CMKBR5
Reactivity
Human, Monkey
(190), (60), (38), (1)
Host
Rabbit
(112), (46), (39), (15), (7), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(17), (13), (12), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF)
(111), (99), (73), (26), (23), (17), (12), (10), (10), (3), (2), (1), (1), (1)
Pubmed 2 references available
Catalog no. ABIN151963
Quantity 0.1 mL
Price
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Immunogen A synthetic peptide demonstrating a high affinity towards the monoclonal CCR5 2D7(see reference 2). This peptide is known as the 2D7-2SK peptide and consists of thefollowing residues: EWQKEGLVTLWLGGGGSC.
Specificity This antibody is specific for CCR5. It demonstrates 2D7-like reactivity. Species Reactivity: This antibody reacts with human and rhesus CCR5 protein. Localization: Membrane, multi pass membrane protein.
Cross-Reactivity Human, Monkey
Alternative Name CD195 / CCR5
Background CCR5 is a major coreceptor for human HIV infection. Alternate Names: anti-CCR5 antibody, anti-CCR 5 antibody, anti-C-C CKR-5 antibody, anti-CC-CKR-5antibody, anti-HIV-1 fusion coreceptor antibody, anti-CHEMR13 antibody, anti-CD195antigen antibody, anti-CMKBR5 antibody.
Gene ID 1234
Research Area CD Antigens, Surface Receptors of Immune Cells, Chemokines, Receptors
Application Notes Suggested working dilutions: flow cytometry / FACS analysis 25 ug/ml,ELISA 1 ug/ml,In vitro assay
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/ml
Buffer 0.1 ml of purified rabbit sera.
Preservative Azide free
Storage 4 °C
General Trkola, Matthews, Gordon et al.: "A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor." in: Journal of virology, Vol. 73, Issue 11, pp. 8966-74, 1999 (PubMed).

Khurana, Kennedy, King et al.: "Identification of a linear peptide recognized by monoclonal antibody 2D7 capable of generating CCR5-specific antibodies with human immunodeficiency virus-neutralizing activity." in: Journal of virology, Vol. 79, Issue 11, pp. 6791-800, 2005 (PubMed).

Hosts (112), (46), (39), (15), (7), (1)
Reactivities (190), (60), (38), (1)
Applications (111), (99), (73), (26), (23), (17), (12), (10), (10), (3), (2), (1), (1), (1)
Conjugates (17), (13), (12), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (14), (14), (14), (8), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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