Aprataxin antibody (APTX) (AA 100-150)

Details for Product anti-APTX Antibody No. ABIN151966, Supplier: Log in to see
Antigen
  • aptx
  • APTX
  • LOC100284636
  • APRATAXIN-like
  • T10O8.20
  • T10O8_20
  • AOA
  • AOA1
  • AXA1
  • EAOH
  • EOAHA
  • FHA-HIT
  • 2410016G21Rik
  • AA388047
  • aprataxin
  • FHA-HIT
  • APRATAXIN-like protein
  • aprataxin L homeolog
  • aptx
  • APTX
  • CpipJ_CPIJ001673
  • LOC100284636
  • aptx.L
  • Aptx
Alternatives
anti-Human Aprataxin antibody for Western Blotting
Epitope
AA 100-150
3
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
50
29
29
6
5
4
3
3
3
3
1
1
Host
Rabbit
43
6
1
Clonality
Polyclonal
Conjugate
This Aprataxin antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunoprecipitation (IP), Western Blotting (WB)
33
18
13
13
6
6
3
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen The immunogen recognized by this antibody maps to a region between residues 100 and 150 of human Aprataxin using the numbering given in SwissProt Entry Q7Z2E3 (GeneID 54840).
Specificity This antibody is specific for human Aprataxin protein.
Purification Immunogen affinity purified
Alternative Name Aprataxin (APTX Antibody Abstract)
Background Gene Symbol: APTX
Gene ID 54840
UniProt Q7Z2E3
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Pathways DNA Damage Repair, Chromatin Binding
Application Notes Western Blot 1:10000-1:25000, Immunoprecipitation 1 - 4 μg/mg lysateOptimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use. Suggested starting dilutions are as follows. Western Blot: 1:10,000 - 1:25,000. Immunoprecipitation: 1 to 4 μg/mg lysate. Histo/Cytochemistry: not tested *In some cases, the antibody may be diluted further than indicated.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer Tris-Citrate/Phosphate ( pH 7.0 - 8.0)
Buffer contains: 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 4°C. Do not freeze.
Supplier Images
Western Blotting (WB) image for anti-Aprataxin (APTX) (AA 100-150) antibody (ABIN151966) Detection of Human Aprataxin by Western Blot. Samples: Whole cell lysate (50 mcg) fro...
Western Blotting (WB) image for anti-Aprataxin (APTX) (AA 100-150) antibody (ABIN151966) Western Blot: Aprataxin Antibody [ABIN151966] - Whole cell lysate (50 ug) from HeLa a...
Western Blotting (WB) image for anti-Aprataxin (APTX) (AA 100-150) antibody (ABIN151966) Western Blot: Aprataxin Antibody - Detection of Human Aprataxin by Western Blot. Sam...
Product cited in: Sykora, Croteau, Bohr, Wilson: "Aprataxin localizes to mitochondria and preserves mitochondrial function." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 18, pp. 7437-42, 2011 (PubMed).

Chu, Qu, Zhong, Artandi, Chang: "Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions." in: Molecular cell, Vol. 44, Issue 4, pp. 667-78, 2011 (PubMed).

Asai, Hirano, Shimada, Kiriyama, Furiya, Ikeda, Iwamoto, Mori, Nishinaka, Konishi, Udaka, Ueno: "Protein kinase C gamma, a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin." in: Human molecular genetics, Vol. 18, Issue 19, pp. 3533-43, 2009 (PubMed).

Biton, Dar, Mittelman, Pereg, Barzilai, Shiloh: "Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 17482-91, 2006 (PubMed).

Luo, Chan, Yang, Rodriguez, Chen, Leng, Mu, Chen, Songyang, Wang, Qin: "A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment." in: Molecular and cellular biology, Vol. 24, Issue 19, pp. 8356-65, 2004 (PubMed).

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