MAD2L1 antibody (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 100-150)

Details for Product anti-MAD2L1 Antibody No. ABIN151995, Supplier: Log in to see
Antigen
  • cb408
  • zgc:112133
  • MAD2L1
  • mad2
  • XMad2
  • AA673185
  • MAD2
  • HSMAD2
  • MAD2 mitotic arrest deficient-like 1 (yeast)
  • MAD2 mitotic arrest deficient-like 1
  • MAD2L1
  • mad2l1
  • LOC100218172
  • Mad2l1
Epitope
AA 100-150
19
8
7
6
4
4
3
3
3
3
2
2
1
1
1
1
1
1
Reactivity
Human
120
36
33
9
6
5
4
4
4
3
3
2
2
1
Host
Rabbit
71
34
15
1
Clonality
Polyclonal
Conjugate
This MAD2L1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
103
46
22
21
20
19
13
5
2
1
1
1
1
1
Options
Supplier
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Immunogen The immunogen recognized by this antibody maps to a region between residues 100 and 150 of human Mitotic Arrest Deficient 2 using the numbering given in SwissProt entry Q13257 (GeneID 4085).
Purification Immunogen affinity purified
Alternative Name MAD2L1 (MAD2L1 Antibody Abstract)
Background Gene Symbol: MAD2L1
Molecular Weight Theoretical MW: 23 kDa
Gene ID 4085
UniProt Q13257
Research Area Cell Cycle
Application Notes Immunohistochemistry 1:1000-1:5000, Immunocytochemistry/Immunofluorescence 1:500 - 1:2500, Immunoprecipitation 2-4 μg/mg lysate, Immunohistochemistry-Paraffin 1:1000-1:5000The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Not for use in: Western Blot
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer Tris-Citrate/Phosphate ( pH 7.0 - 8.0)
Buffer contains: 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 4°C. Do not freeze.
Supplier Images
Western Blotting (WB) image for anti-MAD2L1 antibody (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 100-150) (ABIN151995) Detection of human MAD2 by Western Blot and Immunoprecipitation. Samples: NETN whole ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MAD2L1 antibody (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 100-150) (ABIN151995) Immunohistochemistry-Paraffin: MAD2L1 Antibody [ABIN151995] - Section of human lung c...
Product cited in: McHedlishvili, Wieser, Holtackers, Mouysset, Belwal, Amaro, Meraldi: "Kinetochores accelerate centrosome separation to ensure faithful chromosome segregation." in: Journal of cell science, Vol. 125, Issue Pt 4, pp. 906-18, 2012 (PubMed).

Guccini, Lombardi, Pisani, Piaggi, Scarpato: "Effects of spindle poisons in peripheral human lymphocytes by the in vitro cytokinesis-block micronucleus assay." in: Mutagenesis, Vol. 27, Issue 6, pp. 749-58, 2012 (PubMed).

Matson, Demirel, Stukenberg, Burke: "A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint." in: Genes & development, Vol. 26, Issue 6, pp. 542-7, 2012 (PubMed).

Lince-Faria, Maffini, Orr, Ding, Cláudia Florindo, Sunkel, Tavares, Johansen, Johansen, Maiato: "Spatiotemporal control of mitosis by the conserved spindle matrix protein Megator." in: The Journal of cell biology, Vol. 184, Issue 5, pp. 647-57, 2009 (PubMed).

Yun, Han, Yoon, Kim, Kim, Ju, Kang, Jang, Chung, Lee, Cho, Yoon, Park, Kim, Lee: "p31comet Induces cellular senescence through p21 accumulation and Mad2 disruption." in: Molecular cancer research : MCR, Vol. 7, Issue 3, pp. 371-82, 2009 (PubMed).

Klebig, Korinth, Meraldi: "Bub1 regulates chromosome segregation in a kinetochore-independent manner." in: The Journal of cell biology, Vol. 185, Issue 5, pp. 841-58, 2009 (PubMed).

Chan, Fava, Uldschmid, Schmitz, Gerlich, Nigg, Santamaria: "Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly." in: The Journal of cell biology, Vol. 185, Issue 5, pp. 859-74, 2009 (PubMed).

Wu, Glickstein, Liu, Fujita, Li, Yang, Duvoisin, Wan: "The anaphase-promoting complex coordinates initiation of lens differentiation." in: Molecular biology of the cell, Vol. 18, Issue 3, pp. 1018-29, 2007 (PubMed).

Ito, Mantel, Han, Basu, Fukuda, Cooper, Broxmeyer: "Mad2 is required for optimal hematopoiesis: Mad2 associates with c-Kit in MO7e cells." in: Blood, Vol. 109, Issue 5, pp. 1923-30, 2007 (PubMed).

Agoston, Argani, De Marzo, Hicks, Nelson: "Retinoblastoma pathway dysregulation causes DNA methyltransferase 1 overexpression in cancer via MAD2-mediated inhibition of the anaphase-promoting complex." in: The American journal of pathology, Vol. 170, Issue 5, pp. 1585-93, 2007 (PubMed).

Santamaria, Neef, Eberspächer, Eis, Husemann, Mumberg, Prechtl, Schulze, Siemeister, Wortmann, Barr, Nigg: "Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis." in: Molecular biology of the cell, Vol. 18, Issue 10, pp. 4024-36, 2007 (PubMed).

Vader, Cruijsen, van Harn, Vromans, Medema, Lens: "The chromosomal passenger complex controls spindle checkpoint function independent from its role in correcting microtubule kinetochore interactions." in: Molecular biology of the cell, Vol. 18, Issue 11, pp. 4553-64, 2007 (PubMed).