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Adenomatous Polyposis Coli (APC) (N-Term) antibody

Details for Product No. ABIN152091, Supplier: Log in to see
Antigen
  • AI047805
  • APC1
  • AU020952
  • AW124434
  • BTPS2
  • CC1
  • dp2
  • DP2
  • DP2.5
  • dp2.5
  • DP3
  • dp3
  • fap
  • fpc
  • GS
  • mAPC
  • Min
  • PPP1R46
  • RATAPC
  • xapc
Alternatives
anti-Human Adenomatous Polyposis Coli antibody for Immunocytochemistry
Epitope
N-Term
25
24
21
17
15
14
10
4
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
158
91
60
6
4
2
2
1
1
Host
Mouse
145
36
15
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
9
9
7
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
129
62
61
50
44
27
24
23
12
4
2
1
1
Supplier
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Immunogen Amino acids 1-433 N-terminal fragment of human APC (Adenomutons Polyposis Coli gene Chr 5q) fused to maltose binding protein.
Clone ALi 12-28
Isotype IgG1
Specificity This recognises the N-terminal region of the APC protein.
Cross-Reactivity (Details) Not yet tested in other species.
Purification Protein A purified
Alternative Name APC (APC Antibody Abstract)
Background Gene Symbol: APC
UniProt P25054
Research Area Cell Cycle, Cardiovascular, Coagulation, Transcription Factors, Wnt, Cardiogenesis
Pathways WNT Signaling
Application Notes Western Blot 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.2 mg/mL
Buffer PBS
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Product cited in: Abutaily, Collins, Roche: "Cadherins, catenins and APC in pleural malignant mesothelioma." in: The Journal of pathology, Vol. 201, Issue 3, pp. 355-62, 2003 (PubMed).

Background publications Fodde, Kuipers, Rosenberg, Smits, Kielman, Gaspar, van Es, Breukel, Wiegant, Giles, Clevers: "Mutations in the APC tumour suppressor gene cause chromosomal instability." in: Nature cell biology, Vol. 3, Issue 4, pp. 433-8, 2001 (PubMed).