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THO Complex 4 (THOC4) antibody

Details for Product No. ABIN152094, Supplier: Log in to see
Antigen
  • THOC4
  • Aly
  • ALY
  • ALY/REF
  • BEF
  • REF
  • tho4
  • thoc4
  • zgc:171753
  • Tho4-A
  • alyref-a
  • thoc4-a
  • REF1
  • Refbp1
  • Thoc4
  • Tho4
  • THO complex 4
  • Aly/REF export factor
  • disulfide-isomerase-like
  • THOC4
  • Thoc4
  • ALYREF
  • alyref
  • Alyref
Reactivity
Human, Xenopus laevis
51
20
14
8
3
2
1
1
1
1
Host
Mouse
43
8
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Microarray (MA), ELISA, Western Blotting (WB)
48
31
13
11
10
8
8
2
2
2
1
1
1
1
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Immunogen Recombinant human ALY/ REF protein
Clone 11G5
Isotype IgG1
Specificity This is specific for Aly protein.
Purification Protein A or G purified
Alternative Name Aly (THOC4 Antibody Abstract)
Background Gene Symbol: ALYREF
Gene ID 10189
UniProt Q86V81
Research Area Transcription Factors, Chromatin and Nuclear Signaling
Application Notes Western Blot 0.5-1 μg/mL, ELISA 1:100-1:2000, Immunocytochemistry/Immunofluorescence 1:10-1:2000, Immunoprecipitation 1:10-1:500, MicroarrayCo-immunoprecipitation and western blot studies were performed in Hela cells using a monoclonal mouse anti-Aly antibody. The results indicated that Aly which was observed as a 30 kDa band interacted with the Herpes Simplex Virus I protein, ICP27. 1
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 2.1 mg/mL
Buffer 10 mM PBS ( pH 7.4)
Buffer contains: 15 mM Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-THO Complex 4 (THOC4) antibody (ABIN152094) anti-THO Complex 4 (THOC4) antibody
Product cited in: Okada, Jang, Ye: "Akt phosphorylation and nuclear phosphoinositide association mediate mRNA export and cell proliferation activities by ALY." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 25, pp. 8649-54, 2008 (PubMed).

Majerciak, Yamanegi, Nie, Zheng: "Structural and functional analyses of Kaposi sarcoma-associated herpesvirus ORF57 nuclear localization signals in living cells." in: The Journal of biological chemistry, Vol. 281, Issue 38, pp. 28365-78, 2006 (PubMed).

Kataoka, Dreyfuss: "A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex." in: The Journal of biological chemistry, Vol. 279, Issue 8, pp. 7009-13, 2004 (PubMed).

Zhou, Luo, Straesser, Katahira, Hurt, Reed: "The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans." in: Nature, Vol. 407, Issue 6802, pp. 401-5, 2000 (PubMed).