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Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody

Details for Product No. ABIN152096, Supplier: Log in to see
Antigen
  • D15Ertd119e
  • Hdp
  • hnrnp-A1
  • hnRNP-A1
  • hnRNP A1
  • HNRNPA1
  • HNRPA1
  • Hnrpa1
  • hnrpa1
  • HNRPA1L3
  • ROA1
  • TPT1P
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine)
114
52
34
20
18
4
3
3
1
Host
Mouse
89
26
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
5
5
5
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Microarray (MA), ELISA, Western Blotting (WB)
103
65
42
39
24
23
14
13
2
1
1
Supplier
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Immunogen Full length partially purified human hnRNP A1. [UniProt# P09651]
Clone 4B10
Isotype IgG2a
Specificity Does not react with hnRNP A2 or B
Cross-Reactivity (Details) Not yet tested in other species.
Purification Protein G purified
Alternative Name HnRNP A1 (HNRNPA1 Antibody Abstract)
Background Gene Symbol: HNRNPA1
Gene ID 3178
UniProt P09651
Application Notes Western Blot 0.25 - 0.5 μg/mL, ELISA Indirect, Immunocytochemistry/Immunofluorescence 5 μg/mL, Immunoprecipitation 1:10-1:500, Microarray
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody (ABIN152096) anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody (ABIN152096) Western Blot: hnRNP A1 Antibody (4B10) [ABIN152096] - Whole cell protein from HeLa (l...
Immunofluorescence (IF) image for anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody (ABIN152096) Immunocytochemistry/Immunofluorescence: hnRNP A1 Antibody (4B10) [ABIN152096] - The h...
Product cited in: Kunze, Benz, Brauß, Lampe, Weigand, Braun, Richter, Wittig, Brüne, Schmid: "sST2 translation is regulated by FGF2 via an hnRNP A1-mediated IRES-dependent mechanism." in: Biochimica et biophysica acta, Vol. 1859, Issue 7, pp. 848-59, 2016 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Western Blotting,Immunoprecipitation,Immunofluorescence

Kamelgarn, Chen, Kuang, Arenas, Zhai, Zhu, Gal: "Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS." in: Biochimica et biophysica acta, Vol. 1862, Issue 10, pp. 2004-14, 2016 (PubMed). Further details: Western Blotting

Hu, Khodadadi-Jamayran, Mao, Shah, Yang, Nasim, Wang, Jiang: "AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors." in: Nature communications, Vol. 7, pp. 13347, 2016 (PubMed).

Fujiya, Konishi, Mohamed Kamel, Ueno, Inaba, Moriichi, Tanabe, Ikuta, Ohtake, Kohgo: "microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1." in: Oncogene, Vol. 33, Issue 40, pp. 4847-56, 2014 (PubMed). (Sample species: Human). Further details: Western Blotting

Huelga, Vu, Arnold, Liang, Liu, Yan, Donohue, Shiue, Hoon, Brenner, Ares, Yeo: "Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins." in: Cell reports, Vol. 1, Issue 2, pp. 167-78, 2012 (PubMed). (Sample species: Human).

Lin, Yen: "A novel nucleocytoplasmic shuttling sequence of DAZAP1, a testis-abundant RNA-binding protein." in: RNA (New York, N.Y.), Vol. 12, Issue 8, pp. 1486-93, 2006 (PubMed).

Bonnal, Pileur, Orsini, Parker, Pujol, Prats, Vagner: "Heterogeneous nuclear ribonucleoprotein A1 is a novel internal ribosome entry site trans-acting factor that modulates alternative initiation of translation of the fibroblast growth factor 2 mRNA." in: The Journal of biological chemistry, Vol. 280, Issue 6, pp. 4144-53, 2005 (PubMed). (Sample species: Human). Further details: Western Blotting,Immunoprecipitation

Guil, Gattoni, Carrascal, Abián, Stévenin, Bach-Elias: "Roles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulation." in: Molecular and cellular biology, Vol. 23, Issue 8, pp. 2927-41, 2003 (PubMed). (Sample species: Human). Further details: Western Blotting

Pino, Pío, Toledo, Zabalegui, Vicent, Rey, Lozano, Torre, García-Foncillas, Montuenga: "Altered patterns of expression of members of the heterogeneous nuclear ribonucleoprotein (hnRNP) family in lung cancer." in: Lung cancer (Amsterdam, Netherlands), Vol. 41, Issue 2, pp. 131-43, 2003 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Western Blotting,Immunofluorescence

Mili, Shu, Zhao, Piñol-Roma: "Distinct RNP complexes of shuttling hnRNP proteins with pre-mRNA and mRNA: candidate intermediates in formation and export of mRNA." in: Molecular and cellular biology, Vol. 21, Issue 21, pp. 7307-19, 2001 (PubMed). (Sample species: Human). Further details: Western Blotting

van der Houven van Oordt, Diaz-Meco, Lozano, Krainer, Moscat, Cáceres: "The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation." in: The Journal of cell biology, Vol. 149, Issue 2, pp. 307-16, 2000 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunocytochemistry,Western Blotting,Immunoprecipitation,Immunofluorescence

Del Gatto-Konczak, Olive, Gesnel, Breathnach: "hnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer." in: Molecular and cellular biology, Vol. 19, Issue 1, pp. 251-60, 1999 (PubMed). (Sample species: Human). Further details: Immunoprecipitation

Siomi, Eder, Kataoka, Wan, Liu, Dreyfuss: "Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins." in: The Journal of cell biology, Vol. 138, Issue 6, pp. 1181-92, 1997 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Western Blotting,Immunoprecipitation,Immunofluorescence

Piñol-Roma, Dreyfuss: "Transcription-dependent and transcription-independent nuclear transport of hnRNP proteins." in: Science (New York, N.Y.), Vol. 253, Issue 5017, pp. 312-4, 1991 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Piñol-Roma, Swanson, Gall, Dreyfuss: "A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts." in: The Journal of cell biology, Vol. 109, Issue 6 Pt 1, pp. 2575-87, 1990 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Piñol-Roma, Choi, Matunis, Dreyfuss: "Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins." in: Genes & development, Vol. 2, Issue 2, pp. 215-27, 1988 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Western Blotting,Immunoprecipitation,ELISA,Immunofluorescence

Background publications Vautier, Chesné, Cunha, Calado, Renard, Carmo-Fonseca: "Transcription-dependent nucleocytoplasmic distribution of hnRNP A1 protein in early mouse embryos." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1521-31, 2001 (PubMed).

Izaurralde, Jarmolowski, Beisel, Mattaj, Dreyfuss, Fischer: "A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export." in: The Journal of cell biology, Vol. 137, Issue 1, pp. 27-35, 1997 (PubMed).