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Interleukin 18 Binding Protein (IL18BP) (AA 44-55) antibody

Details for Product No. ABIN152337
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Antigen
Synonyms IL18BP, IL-18BP, Igifbp, MC54L, IL18BPa
Epitope
AA 44-55
(7), (5), (3), (3), (2), (1)
Reactivity
Human
(45), (28), (15), (12), (12)
Host
Rabbit
(47), (9), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
(50), (39), (10), (9), (5), (5), (4), (1), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
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Catalog No. ABIN152337
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Immunogen Amino acid residues 44-55 of human IL-18BP
Specificity IL-18 Binding Protein
Purification affinity purified
Alternative Name IL18BP
Background Interleukin-18 is a cytokine and acts as an early signal in the development of the helperT cell (Th1) response. Interleukin-18 Binding Protein (IL-18BP) binds IL-18 andneutralizes the biological activity of IL-18 in vitro. IL-18BP is expressed in the spleen,belongs to the immunoglobulin superfamily, and has limited homology to the IL-1 type IIreceptor (1). Alternate Names: anti-IL18BPa antibody, anti-interleukin 18 binding protein antibody. Related Diseases: Rheumatoid Arthritis, Inflammation
Gene Symbol: IL18BP
Gene ID 10068
Application Notes IHC-Fr, IHC-P, Immunoprecipitation. Use in western blot reported in scientific literature (PMID 18753296)
Recommended dilutions: Flow Cytometry 1:10-1:1000, Immunocytochemistry/Immunofluorescence 1:10-1:2000, Immunohistochemistry 1:10-1:2000, Immunohistochemistry-Frozen 1:10-1:2000, Immunohistochemistry-Paraffin 1:10-1:2000, Immunoprecipitation 1:10-1:500, Western Blot
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer PBS, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
Supplier Images
anti-Interleukin 18 Binding Protein (IL18BP) (AA 44-55) antibody anti-Interleukin 18 Binding Protein (IL18BP) (AA 44-55) antibody
General Novick, Kim, Fantuzzi et al.: "Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response." in: Immunity, Vol. 10, Issue 1, pp. 127-36, 1999 (PubMed).

He, Lu, Altmann et al.: "Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury." in: American journal of physiology. Renal physiology, Vol. 295, Issue 5, pp. F1414-21, 2008 (PubMed).

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