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Interleukin 18 Binding Protein (IL18BP) (AA 44-55) antibody

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AA 44-55
(13), (13), (11), (4), (3), (2), (2), (2), (1), (1), (1)
(62), (40), (24)
(72), (11), (10)
(12), (6), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
(64), (51), (13), (11), (9), (9), (9), (4), (4), (2), (2), (1), (1)
Pubmed 2 references available
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Quantity 0.1 mg
Shipping to United States ( )
Immunogen Amino acid residues 44-55 of human IL-18BP
Specificity IL-18 Binding Protein
Purification affinity purified
Alternative Name IL18BP (IL18BP Antibody Abstract)
Background Interleukin-18 is a cytokine and acts as an early signal in the development of the helperT cell (Th1) response. Interleukin-18 Binding Protein (IL-18BP) binds IL-18 andneutralizes the biological activity of IL-18 in vitro. IL-18BP is expressed in the spleen,belongs to the immunoglobulin superfamily, and has limited homology to the IL-1 type IIreceptor (1). Alternate Names: anti-IL18BPa antibody, anti-interleukin 18 binding protein antibody. Related Diseases: Rheumatoid Arthritis, Inflammation
Gene Symbol: IL18BP
Gene ID 10068
Application Notes IHC-Fr, IHC-P, Immunoprecipitation. Use in western blot reported in scientific literature (PMID 18753296)
Recommended dilutions: Flow Cytometry 1:10-1:1000, Immunocytochemistry/Immunofluorescence 1:10-1:2000, Immunohistochemistry 1:10-1:2000, Immunohistochemistry-Frozen 1:10-1:2000, Immunohistochemistry-Paraffin 1:10-1:2000, Immunoprecipitation 1:10-1:500, Western Blot
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer PBS, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
Supplier Images
ELISA image for anti-Interleukin 18 Binding Protein (IL18BP) (AA 44-55) antibody (ABIN152337) anti-Interleukin 18 Binding Protein (IL18BP) (AA 44-55) antibody
Product cited in: He, Lu, Altmann et al.: "Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury." in: American journal of physiology. Renal physiology, Vol. 295, Issue 5, pp. F1414-21, 2008 (PubMed).

Background publications Novick, Kim, Fantuzzi et al.: "Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response." in: Immunity, Vol. 10, Issue 1, pp. 127-36, 1999 (PubMed).

Catalog No. ABIN152337

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