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Details for Product No. ABIN152337

Interleukin 18 Binding Protein (IL18BP) antibody

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Antigen
Synonyms IL18BPa, MC54L, Igifbp, IL-18BP, IL18BP
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
Pubmed 2 references available
Catalog no. ABIN152337
Quantity 0.1 mg
Price
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Immunogen Amino acid residues 44-55 of human IL-18BP [STKDPCPSQPPVC].
Specificity Species Reactivity: Reacts with human. Localization: Secreted.
Cross-Reactivity Human
Purification Purified
Alternative Name IL18BP
Background Interleukin-18 is a cytokine and acts as an early signal in the development of the helperT cell (Th1) response. Interleukin-18 Binding Protein (IL-18BP) binds IL-18 andneutralizes the biological activity of IL-18 in vitro. IL-18BP is expressed in the spleen,belongs to the immunoglobulin superfamily, and has limited homology to the IL-1 type IIreceptor (1). Alternate Names: anti-IL18BPa antibody, anti-interleukin 18 binding protein antibody. Related Diseases: Rheumatoid Arthritis, Inflammation
Gene ID 10068
Application Notes Suggested working dilutions: Western Blot - 1:500-1:1,000
Restrictions For Research Use only
Concentration 1.0 mg/ml
Buffer PBS. Preservative: Sodium Azide.
Preservative Sodium azide
Storage 4 °C
Novick, Kim, Fantuzzi et al.: "Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response." in: Immunity, Vol. 10, Issue 1, pp. 127-36, 1999 (PubMed).

He, Lu, Altmann et al.: "Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury." in: American journal of physiology. Renal physiology, Vol. 295, Issue 5, pp. F1414-21, 2008 (PubMed).

Alternatives for antigen "Interleukin 18 Binding Protein (IL18BP)", type "Antibodies"
Hosts (41), (10), (2)
Reactivities (32), (31), (13), (12), (12)
Applications (40), (33), (10), (6), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Conjugates (7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (3), (2), (1)
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