Estrogen Receptor 2 (ER Beta) (ESR2) (AA 1-153) antibody

Details for Product No. ABIN152348
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Antigen
Synonyms
ER[b]1, zfER-beta1, zfER[b]1, erb, esrb, estrb, nr3a2, ERbeta, er-beta, esr-beta, ESR2, er, esr2, erb2, erb1, ER-beta, ER[b], Estrb, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2, Erb2, ERB, ERBETA, CERB ... show more
ER[b]1, zfER-beta1, zfER[b]1, erb, esrb, estrb, nr3a2, ERbeta, er-beta, esr-beta, ESR2, er, esr2, erb2, erb1, ER-beta, ER[b], Estrb, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2, Erb2, ERB, ERBETA, CERB, ERBeta2, erbeta, Esr2 show less
Epitope
AA 1-153
(25), (22), (19), (19), (17), (14), (11), (9), (7), (6), (6), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(218), (90), (78), (26), (25), (13), (3), (1), (1), (1)
Host
Mouse
(199), (37), (5), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(13), (10), (9), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1)
Application
Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
(178), (74), (49), (40), (35), (35), (24), (22), (17), (7), (3), (3), (1), (1)
Pubmed 4 references available
Quantity 0.1 mg
Shipping to United States (Change)
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Catalog No. ABIN152348
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Immunogen Amino acids 1-153 of human ER-Beta expressed in E. coli.
Clone 6A12
Isotype IgG2b
Specificity This is specific for Estrogen receptor-Beta.
Purification Protein G purified
Alternative Name Estrogen receptor beta
Background The human ER-. Alternate Names: anti-ER beta antibody.
Gene Symbol: ESR2
Gene ID 2100
Application Notes By Western blot, this antibody recognizes ER-beta. Suggested working dilutions: *Western Blot 1-5 µg/ml. *The investigator should determine the optimal working dilution for a specific application. Chromatin Immunoprecipitation was reported in scientific literature.
Recommended dilutions: Chromatin Immunoprecipitation, Immunocytochemistry/Immunofluorescence 1:10-1:2000, Immunohistochemistry 1:10-1:2000, Immunohistochemistry-Frozen 1:10-1:2000, Immunohistochemistry-Paraffin 1:10-1:2000, Immunoprecipitation 1:10-1:500, Western Blot 1-5 µg/mL
Restrictions For Research Use only
Buffer PBS [pH 7.4] contains no preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Aliquot and store at -20 °C or -80 °C.
General Speirs, Skliris, Burdall et al.: "Distinct expression patterns of ER alpha and ER beta in normal human mammary gland." in: Journal of clinical pathology, Vol. 55, Issue 5, pp. 371-4, 2002 (PubMed).

Saji, Omoto, Shimizu et al.: "Expression of estrogen receptor (ER) (beta)cx protein in ER(alpha)-positive breast cancer: specific correlation with progesterone receptor." in: Cancer research, Vol. 62, Issue 17, pp. 4849-53, 2002 (PubMed).

Bianco, Perry, Smith et al.: "Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage." in: Molecular endocrinology (Baltimore, Md.), Vol. 17, Issue 7, pp. 1344-55, 2003 (PubMed).

Konstantinopoulos, Kominea, Vandoros et al.: "Oestrogen receptor beta (ERbeta) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation." in: European journal of cancer (Oxford, England : 1990), Vol. 39, Issue 9, pp. 1251-8, 2003 (PubMed).

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