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tyrosine Hydroxylase (TH) antibody

Details for Product No. ABIN152458, Supplier: Log in to see
Antigen
  • CG10118
  • DH65B
  • DTH
  • Dmel\\CG10118
  • Pale
  • Ple
  • TH
  • Th
  • VII
  • dTH1
  • dTH65B
  • pale/ple
  • th
  • 14-3-3
  • 14-3-3 epsilon
  • 14-3-3-e
  • 14-3-3-epsilon
  • 14-3-30epsilon
  • 14-3-3EPSILON
  • 14-3-3e
  • 14-3-3omicron
  • 1433epsilon
  • 143E_DROME
  • CG31196
  • CT24092
  • D14-3-3e
  • D14-3-3epsilon
  • Dmel\\CG31196
  • EK3-5
  • PAR-5
  • PAR5
  • Par-5
  • SR3-9
  • Su(Raf)3B
  • anon-WO0172774.141
  • anon-WO02059370.52
  • d14-3-3epsilon
  • eps
  • l(3)j2B10
  • par-5
  • DYT14
  • DYT5b
  • TYH
  • The
  • pale
  • tyrosine 3-monooxygenase
  • CG31196 gene product from transcript CG31196-RB
  • tyrosine hydroxylase
  • ple
  • th
  • Tsp_12013
  • 14-3-3epsilon
  • TH
  • Th
Reactivity
Fruit Fly (Drosophila melanogaster), Human, Mammalian, Mouse (Murine), Rat (Rattus)
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15
12
7
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Host
Rabbit
246
107
17
15
8
Clonality
Polyclonal
Conjugate
Un-conjugated
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6
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4
4
3
3
3
3
3
3
3
3
3
3
3
1
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Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Free Floating) (IHC (ff)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Simple Western (SimWes), Western Blotting (WB)
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92
77
66
65
53
32
11
7
4
4
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2
1
1
Options
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Available images

Immunogen SDS-denatured, native rat tyrosine hydroxylase purified from pheochromocytoma
Specificity Specific for the ~60k tyrosine hydroxylase protein.
Purification Immunogen affinity purified
Alternative Name Tyrosine Hydroxylase (TH Antibody Abstract)
Background Gene Symbol: TH
Molecular Weight Theoretical MW: 60 kDa
Gene ID 7054
UniProt P07101
Research Area Enzymes, Amino Acids, Cancer
Application Notes Western Blot 1:1000, Simple Western 2 μg/mL, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:1000, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:1000, Immunohistochemistry Free-FloatingImmunohistochemistry: use reported in literature (PMID: 22262884 and PMID: 23811324). Use in rat and mouse reported in customer review. Use in Immunohistochemistry-Free floating reported in scientific literature (PMID 25731749) In Simple Western only 10 - 15 μL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.15 mg/mL
Buffer 10 mM HEPES ( pH 7.5), 0.15M NaCl, 0.1 mg/mL BSA and 50 % Glycerol
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Immunofluorescence (IF) image for anti-tyrosine Hydroxylase (TH) antibody (ABIN152458) Immunohistochemical staining of retina tissue during ABIN152458.
Immunofluorescence (IF) image for anti-tyrosine Hydroxylase (TH) antibody (ABIN152458) Immunocytochemistry/Immunofluorescence: Tyrosine Hydroxylase Antibody [ABIN152458] - ...
Immunofluorescence (IF) image for anti-tyrosine Hydroxylase (TH) antibody (ABIN152458) Immunocytochemistry/Immunofluorescence: Tyrosine Hydroxylase Antibody [ABIN152458] - ...
Immunofluorescence (IF) image for anti-tyrosine Hydroxylase (TH) antibody (ABIN152458) Immunocytochemistry/Immunofluorescence: Tyrosine Hydroxylase Antibody [ABIN152458] - ...
Immunofluorescence (IF) image for anti-tyrosine Hydroxylase (TH) antibody (ABIN152458) Immunocytochemistry/Immunofluorescence: Tyrosine Hydroxylase Antibody [ABIN152458] - ...
Western Blotting (WB) image for anti-tyrosine Hydroxylase (TH) antibody (ABIN152458) Western Blot: Tyrosine Hydroxylase Antibody [ABIN152458] - WB analysis of Tyrosine Hy...
Western Blotting (WB) image for anti-tyrosine Hydroxylase (TH) antibody (ABIN152458) Western Blot: Tyrosine Hydroxylase Antibody [ABIN152458] - 10 ug of rat caudate lysat...
Simple Western (SimWes) image for anti-tyrosine Hydroxylase (TH) antibody (ABIN152458) Simple Western: Tyrosine Hydroxylase Antibody [ABIN152458] - Simple Western lane view...
Product cited in: van der Keylen, Garreis, Steigleder, Sommer, Neuhuber, Wörl: "Involvement of catecholaminergic neurons in motor innervation of striated muscle in the mouse esophagus." in: Histochemistry and cell biology, Vol. 145, Issue 5, pp. 573-85, 2016 (PubMed).

Karuppagounder, Xiong, Lee, Lawless, Kim, Nordquist, Martin, Ge, Brahmachari, Jhaldiyal, Kumar, Andrabi, Dawson, Dawson: "LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity." in: Journal of chemical neuroanatomy, Vol. 76, Issue Pt B, pp. 90-97, 2016 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Free Floating)

Perry, Carter, Cushing: "Chronic social isolation enhances reproduction in the monogamous prairie vole (Microtus ochrogaster)." in: Psychoneuroendocrinology, Vol. 68, pp. 20-8, 2016 (PubMed). Further details: Immunohistochemistry (Free Floating)

Lin, Hsieh, Chen, Wu, Tsai, Huang, Hua, Wei, Yeh, Liu: "Non-invasive, neuron-specific gene therapy by focused ultrasound-induced blood-brain barrier opening in Parkinson's disease mouse model." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 235, pp. 72-81, 2016 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Frozen Sections)

Kniewallner, Wenzel, Humpel: "Thiazine Red(+) platelet inclusions in Cerebral Blood Vessels are first signs in an Alzheimer's Disease mouse model." in: Scientific reports, Vol. 6, pp. 28447, 2016 (PubMed).

Cowburn, Crosby, Macias, Branco, Colaço, Southwood, Toshner, Crotty Alexander, Morrell, Chilvers, Johnson: "HIF2α-arginase axis is essential for the development of pulmonary hypertension." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 31, pp. 8801-6, 2016 (PubMed). Further details: Immunocytochemistry,Immunofluorescence

Januchowski, Wojtowicz, Sterzyńska, Sosińska, Andrzejewska, Zawierucha, Nowicki, Zabel: "Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines." in: The international journal of biochemistry & cell biology, Vol. 78, pp. 248-59, 2016 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunohistochemistry

Hamanaka, Minoura, Nishino, Miura, Mizunami: "Dopamine- and Tyrosine Hydroxylase-Immunoreactive Neurons in the Brain of the American Cockroach, Periplaneta americana." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160531, 2016 (PubMed). (Sample species: Insect). Further details: Immunocytochemistry,Western Blotting,Immunofluorescence,Immunohistochemistry

Jiang, Kang, Zhang, Karuppagounder, Xu, Lee, Kang, Lee, Zhang, Pletnikova, Troncoso, Pirooznia, Andrabi, Dawson, Dawson: "Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons." in: eNeuro, Vol. 3, Issue 4, 2016 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunohistochemistry

Ishizu, Yui, Hebisawa, Aizawa, Cui, Fujita, Hashimoto, Ajioka, Mizusawa, Yokota, Watase: "Impaired striatal dopamine release in homozygous Vps35 D620N knock-in mice." in: Human molecular genetics, 2016 (PubMed). Method employed by authors: Immunohistochemistry (IHC)

Grier, Belluscio, Cheetham: "Olfactory Sensory Activity Modulates Microglial-Neuronal Interactions during Dopaminergic Cell Loss in the Olfactory Bulb." in: Frontiers in cellular neuroscience, Vol. 10, pp. 178, 2016 (PubMed). Method employed by authors: Western Blotting (WB)

Tsika, Nguyen, Dusonchet, Colin, Schneider, Moore: "Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease." in: Neurobiology of disease, Vol. 77, pp. 49-61, 2015 (PubMed). (Sample species: Rat (Rattus)). Further details: Western Blotting,Immunohistochemistry (Free Floating)

Li, Sagot, Zhou et al.: "Similar L-dopa-stimulated motor activity in mice with adult-onset 6-hydroxydopamine-induced symmetric dopamine denervation and in transcription factor Pitx3 null mice with perinatal-onset symmetric ..." in: Brain research, Vol. 1615, pp. 12-21, 2015 (PubMed). (Sample species: Mouse (Murine)).

Kuo, Wu, Hsieh, Lin, Wen, Chen, Chen, Yu, Wang, Su, Lin, Yang, Guan, Wang, Lan, Fu: "PPL2ab neurons restore sexual responses in aged Drosophila males through dopamine." in: Nature communications, Vol. 6, pp. 7490, 2015 (PubMed). (Sample species: Fruit Fly (Drosophila melanogaster)). Further details: Immunohistochemistry (Whole Mount)

Liu, Li, Jalewa, Saunders-Wood, Li, Hölscher: "Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's disease." in: European journal of pharmacology, Vol. 765, pp. 284-90, 2015 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Stevens, Lee, Kang, Lee, Lee, Bower, Jiang, Kang, Andrabi, Dawson, Shin, Dawson: "Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 37, pp. 11696-701, 2015 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunocytochemistry,Western Blotting,Immunohistochemistry (Free Floating),Immunofluorescence

Bains, Roberts: "Estrogen protects against dopamine neuron toxicity in primary mesencephalic cultures through an indirect P13K/Akt mediated astrocyte pathway." in: Neuroscience letters, Vol. 610, pp. 79-85, 2015 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunocytochemistry,Immunofluorescence

Platero-Luengo, González-Granero, Durán, Díaz-Castro, Piruat, García-Verdugo, Pardal, López-Barneo: "An O2-sensitive glomus cell-stem cell synapse induces carotid body growth in chronic hypoxia." in: Cell, Vol. 156, Issue 1-2, pp. 291-303, 2014 (PubMed). Further details: Immunohistochemistry (Frozen Sections)

Tsika, Glauser, Moser, Fiser, Daniel, Sheerin, Lees, Troncoso, Lewis, Bandopadhyay, Schneider, Moore: "Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration." in: Human molecular genetics, Vol. 23, Issue 17, pp. 4621-38, 2014 (PubMed). (Sample species: Rat (Rattus)). Further details: Immunocytochemistry,Western Blotting,Immunofluorescence

Grünewald, Lax, Rocha, Reeve, Hepplewhite, Rygiel, Taylor, Turnbull: "Quantitative quadruple-label immunofluorescence of mitochondrial and cytoplasmic proteins in single neurons from human midbrain tissue." in: Journal of neuroscience methods, Vol. 232, pp. 143-9, 2014 (PubMed).