Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1) antibody

Details for Product No. ABIN152474
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Antigen
Synonyms NCX1, AI852629, AV344025, D930008O12Rik, Ncx1, Ncx, SLC8A1, ncx1n
Reactivity
Rabbit
(29), (27), (25), (22), (18), (18), (17), (17), (10), (2)
Host
Mouse
(29), (17)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(29), (20), (10), (9), (8), (4), (4), (3), (3)
Pubmed 3 references available
Catalog no. ABIN152474
Quantity 0.1 mg
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Immunogen Fusion protein from N-terminus of rabbit renal Na/Ca exchanger.
Isotype IgG2b
Specificity Reacts with the Na(+)/Ca(2+)- exchanger in a number of species and tissues. Thisantibody has been used on rat, mouse, human, bovine, and rabbit tissue. Species Reactivity: Bovine, human, mouse, rat, rabbit. Localization: Plasma Membrane.
Cross-Reactivity Mammalian
Purification Purified
Alternative Name SLC8A1 / NCX1
Background The expression and protein levels of the Na(+)/Ca(2+) exchanger (NCX-1) vary duringheart development and in response to changes in thyroid hormone levels (1). Theexpression of the NCX-1 gene is two-fold higher in the hearts of fetal versus adult mice. In addition, NCX-1 mRNA and protein levels were upregulated in hypothyroidic hearts. In hyperthyroidic hearts this response was reversed, however. Alternate Names: Anti-CNC antibody, Anti-DKFZp779F0871 antibody, Anti-MGC119581 antibody,Anti-Na+/Ca2+ exchange protein 1 antibody, Anti-Na+/Ca2+ exchanger antibody,Anti-NCX 1 antibody, Anti-NCX antibody, Anti-SLC8A1 antibody, Anti-SLC8A1 proteinantibody, Anti-Sodium Calcium Exchanger antibody, Anti-Sodium/calcium exchanger 1antibody, Anti-Solute carrier family 8 member 1 antibody.
Gene ID 6546, 20541, 29715
Application Notes Suggested working dilutions: immunohistochemistry 1/2001/1000,Western Blot 1/200
Restrictions For Research Use only
Buffer Phosphate buffered saline. Preservative: no preservative.
Storage -20 °C
Supplier Images
anti-Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1) antibody Western blot of various tissues showing specific immunolabeling of the ~120k and ~160k NaCX-1 protein. Lane 1 - Brain, Lane 2 - Heart, Lane 3 - Kidney, Lane 4 - Lung, Lane 5 - Spleen.
General Beaugue, Asteggiano, Berberiuan: "Regulation of phosphatidylinositol-4,5-biphosphate bound to the bovine cardiac Na+/Ca2+ exchanger." in: Annals of the New York Academy of Sciences, Vol. 976, pp. 288-99, 2002 (PubMed).

Sears, Bryant, Ashley et al.: "Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling." in: Circulation research, Vol. 92, Issue 5, pp. e52-9, 2003 (PubMed).

Vagin, Tokhtaeva, Yakubov et al.: "Inverse correlation between the extent of N-glycan branching and intercellular adhesion in epithelia. Contribution of the Na,K-ATPase beta1 subunit." in: The Journal of biological chemistry, Vol. 283, Issue 4, pp. 2192-202, 2008 (PubMed).

Hosts (29), (17)
Reactivities (29), (27), (25), (22), (18), (18), (17), (17), (10), (2)
Applications (29), (20), (10), (9), (8), (4), (4), (3), (3)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (3), (2), (1), (1), (1)
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