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PCLO antibody (PE)

PCLO Reactivity: Human FACS Host: Mouse Monoclonal PCLO-01 PE
Catalog No. ABIN1526067
  • Target See all PCLO Antibodies
    PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
    Reactivity
    • 11
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 17
    • 1
    Mouse
    Clonality
    • 15
    • 3
    Monoclonal
    Conjugate
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCLO antibody is conjugated to PE
    Application
    • 17
    • 11
    • 10
    • 10
    • 4
    Flow Cytometry (FACS)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Size-exclusion chromatography
    Clone
    PCLO-01
    Isotype
    IgG1
    Top Product
    Discover our top product PCLO Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), 15 mM sodium azide, 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA)
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
    Alternative Name
    PCLO (PCLO Products)
    Synonyms
    pclo antibody, wu:fj53e09 antibody, Acz antibody, Pico antibody, mKIAA0559 antibody, aczonin antibody, PCLO antibody, ACZ antibody, piccolo presynaptic cytomatrix protein antibody, piccolo presynaptic cytomatrix protein a antibody, piccolo (presynaptic cytomatrix protein) antibody, PCLO antibody, pcloa antibody, Pclo antibody, LOC768552 antibody
    Background
    PCLO (piccolo, also known as aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion.Synonyms: ACZ, Aczonin, KIAA0559, Protein piccolo
    Pathways
    Hormone Transport, Synaptic Vesicle Exocytosis
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