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beta Catenin antibody (Catenin, beta) (pSer33)

Details for Product anti-Catenin, beta Antibody No. ABIN152613, Supplier: Log in to see
Antigen
  • armadillo
  • beta-catenin
  • Bfc
  • Catnb
  • CHBCAT
  • CTNNB
  • ctnnb
  • ctnnb1
  • id:ibd2058
  • Mesc
  • MRD19
  • wu:fb73e10
  • wu:fi81c06
  • wu:fk25h01
Epitope
pSer33, pSer37
54
51
35
32
31
23
20
16
16
15
15
15
14
14
12
5
5
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
434
332
302
29
18
18
16
16
11
10
10
9
7
6
6
2
1
1
Host
Rabbit
332
101
4
4
Clonality
Polyclonal
Conjugate
This beta Catenin antibody is un-conjugated
17
15
14
11
10
10
10
9
9
9
9
9
4
4
3
3
3
3
3
3
3
3
1
1
1
1
1
1
Application
Western Blotting (WB)
303
155
109
99
86
83
80
67
61
13
11
3
3
1
1
1
1
Supplier
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Immunogen Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser33/37 conjugated to KLH
Specificity Specific for the ~83k beta-catenin phosphorylated at Ser33 and Ser37.
Cross-Reactivity (Details) Tested in Human. Reactivity assumed based on 100% sequence identity: Mouse, Rat,Xenopus.
Purification Immunogen affinity purified
Alternative Name beta-Catenin
Background Gene Symbol: CTNNB1
UniProt P35222
Application Notes Western Blot 1:1000
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer 10 mM HEPES ( pH 7.5), 150 mM NaCl, 0.1 mg/mL BSA and 50 % glycerol
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-beta Catenin antibody (Catenin, beta) (pSer33) (ABIN152613) Western Blot of human embryonic kidney cell (HEK) lysate showing immunolabeling with ...
Product cited in: Wang, Vogelstein, Kinzler: "Phosphorylation of beta-catenin at S33, S37, or T41 can occur in the absence of phosphorylation at T45 in colon cancer cells." in: Cancer research, Vol. 63, Issue 17, pp. 5234-5, 2003 (PubMed).

Ding, Dale: "Wnt signal transduction: kinase cogs in a nano-machine?" in: Trends in biochemical sciences, Vol. 27, Issue 7, pp. 327-9, 2002 (PubMed).

Liu, Li, Semenov, Han, Baeg, Tan, Zhang, Lin, He: "Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism." in: Cell, Vol. 108, Issue 6, pp. 837-47, 2002 (PubMed).

Polakis: "Wnt signaling and cancer." in: Genes & development, Vol. 14, Issue 15, pp. 1837-51, 2000 (PubMed).