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CHEK2 antibody (pThr383)

CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1531498
  • Target See all CHEK2 Antibodies
    CHEK2 (Checkpoint Kinase 2 (CHEK2))
    Binding Specificity
    • 30
    • 28
    • 21
    • 17
    • 16
    • 15
    • 15
    • 15
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-405, pThr383
    Reactivity
    • 260
    • 95
    • 81
    • 16
    • 14
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 241
    • 20
    • 1
    • 1
    Rabbit
    Clonality
    • 227
    • 36
    Polyclonal
    Conjugate
    • 115
    • 14
    • 12
    • 12
    • 12
    • 12
    • 12
    • 12
    • 10
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    This CHEK2 antibody is un-conjugated
    Application
    • 205
    • 80
    • 79
    • 71
    • 37
    • 35
    • 33
    • 28
    • 28
    • 19
    • 18
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Specificity

    Chk2 (Phospho-Thr383) Antibody detects endogenous levels of Chk2 only when phosphorylated at Thr383.

    PhosphorylationH:T383 M:T387 R:T386

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Purity
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human Chk2 around the phosphorylation site of Thr383.
    Isotype
    IgG
    Top Product
    Discover our top product CHEK2 Primary Antibody
  • Application Notes
    WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:20000
    Comment

    Unigene-Number: Hs.291363, Hs.505297 (NCBI Gene Symbol: CHEK2)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Stable at -20°C for at least 1 year.
    Expiry Date
    12 months
  • Target
    CHEK2 (Checkpoint Kinase 2 (CHEK2))
    Alternative Name
    Chk2 (CHEK2 Products)
    Synonyms
    CDS1 antibody, CHK2 antibody, HuCds1 antibody, LFS2 antibody, PP1425 antibody, RAD53 antibody, hCds1 antibody, fa66f08 antibody, wu:fa66f08 antibody, zgc:55865 antibody, Cds1 antibody, HUCDS1 antibody, Rad53 antibody, Chk2 antibody, cds1 antibody, chek2 antibody, chk2 antibody, hucds1 antibody, lfs2 antibody, pp1425 antibody, rad53 antibody, checkpoint kinase 2 antibody, serine/threonine-protein kinase chk2 antibody, checkpoint kinase 2 L homeolog antibody, CHEK2 antibody, chek2 antibody, Chek2 antibody, MCYG_07308 antibody, chek2.L antibody
    Background

    Synonyms: Cds1, CHEK2, CHK2, Chk2, CHK2 checkpoint homolog (S. pombe), kinase Chk2, RAD53

    NCBI Gene Symbol: CHEK2

    Molecular Weight
    60 kDa
    Gene ID
    11200
    OMIM
    176807
    UniProt
    O96017
    Pathways
    p53 Signaling, Apoptosis, Cell Division Cycle
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