Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Add to Basket
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN152675

DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) antibody

Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms ICF, ICF1, M.HsaIIIB, cb91, dnmt3bl, dnmt7, sb:cb91, wu:fb16h07, cb633, dnmt3b, DNMT3B, LOC100218113
»Alternatives Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN152675
Quantity 0.1 mg
Contact our Customer Service for availability and price in your country.
Shipping to
Immunogen Synthetic peptide: MKGDSRHLNEEEGA-C, corresponding to amino acids 1-14 ofMouse Dnmt3b.
Specificity This antibody detects DNA methyltransferase 3b (Dnmt3b) from human and mousetissues and cells as well as recombinant human Dnmt3b. This antibody detects, to alesser extent, full-length human recombinant Dnmt3a. Species Reactivity: Cross-reacts with Human and Mouse. Not yet tested in other species. Localization: Nuclear.
Cross-Reactivity Human, Mouse (Murine)
Purification Aff - Purified
Alternative Name DNMT3B
Background DNA methyltransferases methylate the 5-position of cytosine in the context of CpGdinucleotides. DNA methylation is crucial for normal embryonic development, geneticimprinting, and X-chromosome inactivation. Hypermethylation of DNA has also beenimplicated in tumorigenesis through improper methylation of growth regulatory genepromoter regions. Alternate Names: anti-ICF antibody, anti-M.HsaIIIB antibodyCytosine 5methyltransferase 3B antibody,anti- DNA (cytosine 5) methyltransferase 3 beta antibody. anti- DNA antibody, anti- DNAmethyltransferase HsaIIIB antibody, anti- EC antibody, anti- ICF antibody, anti-M.HsaIIIB antibody.
Gene ID 1789, 13436
Application Notes Suggested working dilutions: chromatin immunoprecipitation 2ug/106,Western Blot 2.0 ug/ml. Positive Controls: P19 nuclear extracts.
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS with 1 mg/ml BSA
Storage -20 °C
Okano, Bell, Haber et al.: "DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development." in: Cell, Vol. 99, Issue 3, pp. 247-57, 1999 (PubMed).

Alternatives for antigen "DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B)", type "Antibodies"
Hosts (39), (10), (5)
Reactivities (49), (15), (4), (1), (1), (1), (1)
Applications (52), (18), (16), (15), (14), (13), (12), (5), (2), (2), (1)
Epitopes (8), (2), (2), (2), (2), (1), (1), (1), (1)