Prolactin Receptor antibody (PRLR)

Details for Product anti-PRLR Antibody No. ABIN152720, Supplier: Log in to see
Antigen
  • PRL-R
  • prlr
  • PRLR
  • tprlr
  • DKFZp469D061
  • hPRLrI
  • AI987712
  • Pr-1
  • Pr-3
  • Prlr-rs1
  • RATPRLR
  • PRLRb
  • prolactin receptor
  • prlr-a
  • prlr-b
  • PRLR
  • prlr
  • Prlr
  • PR
Alternatives
anti-Human Prolactin Receptor antibody for Enzyme Immunoassay
Reactivity
Cow (Bovine), Hamster, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
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66
35
16
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12
2
2
2
2
1
Host
Mouse
160
68
6
4
Clonality (Clone)
Monoclonal ()
Conjugate
This Prolactin Receptor antibody is un-conjugated
7
7
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6
6
6
6
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6
6
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4
2
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
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50
13
4
2
2
2
2
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Purified rat liver PRL receptor.
Clone U5
Isotype IgG1
Purification Protein G purified
Alternative Name Prolactin R (PRLR Antibody Abstract)
Background Gene Symbol: PRLR
Gene ID 5618
UniProt P16471
Pathways JAK-STAT Signaling, Response to Growth Hormone Stimulus
Application Notes Western Blot 1 μg/mL, Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Immunoprecipitation 1:10 - 1:500, Immunohistochemistry-Paraffin 1:10 - 1:500, Immunohistochemistry-Frozen 1:10 - 1:500, Immunofluorescence 1:20, Immunocytochemistry 5 μg/mLMay be useful in IHC, IP, and WB. WB: Detects an approx. 40 kDa and 100 kDa protein representing both the short and long forms of the PRL receptor, respectively, in various tissues. IHC: Staining of PRL receptor in rat Islets of Langerhans with NB 300-561 results in a staining pattern consistent with cytoplasmic vesicle staining. NB 300-561, after biotinylation, has been used to detect human lymphocyte PRL receptor by Flow Cytometry. NB 300-561 does not inhibit the interaction of prolactin with the receptor.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute with 0.1 mL PBS.
Buffer No buffer
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Immunofluorescence (IF) image for anti-Prolactin Receptor (PRLR) antibody (ABIN152720) Figure 1 shows immunohistochemical staining of PRL receptor in rat Islets of Langerha...
Immunohistochemistry (IHC) image for anti-Prolactin Receptor (PRLR) antibody (ABIN152720) Immunohistochemistry: Prolactin R Antibody (U5) [ABIN152720] - Mammary gland tissue f...
Immunofluorescence (IF) image for anti-Prolactin Receptor (PRLR) antibody (ABIN152720) Immunocytochemistry/Immunofluorescence: Prolactin R Antibody (U5) [ABIN152720] - Prol...
Immunofluorescence (IF) image for anti-Prolactin Receptor (PRLR) antibody (ABIN152720) Immunocytochemistry/Immunofluorescence: Prolactin R Antibody (U5) [ABIN152720] - Prol...
Immunofluorescence (IF) image for anti-Prolactin Receptor (PRLR) antibody (ABIN152720) Immunocytochemistry/Immunofluorescence: Prolactin R Antibody (U5) [ABIN152720] - Prol...
Product cited in: Perrot-Applanat, Gualillo, Buteau, Edery, Kelly: "Internalization of prolactin receptor and prolactin in transfected cells does not involve nuclear translocation." in: Journal of cell science, Vol. 110 ( Pt 9), pp. 1123-32, 1997 (PubMed).

Royster, Driscoll, Kelly, Freemark: "The prolactin receptor in the fetal rat: cellular localization of messenger ribonucleic acid, immunoreactive protein, and ligand-binding activity and induction of expression in late gestation." in: Endocrinology, Vol. 136, Issue 9, pp. 3892-900, 1995 (PubMed).

Sorenson, Stout: "Prolactin receptors and JAK2 in islets of Langerhans: an immunohistochemical analysis." in: Endocrinology, Vol. 136, Issue 9, pp. 4092-8, 1995 (PubMed).

Rui, Lebrun, Kirken, Kelly, Farrar: "JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization." in: Endocrinology, Vol. 135, Issue 4, pp. 1299-306, 1994 (PubMed).

Dardenne, de Moraes, Kelly, Gagnerault: "Prolactin receptor expression in human hematopoietic tissues analyzed by flow cytofluorometry." in: Endocrinology, Vol. 134, Issue 5, pp. 2108-14, 1994 (PubMed).

Gagnerault, Touraine, Savino, Kelly, Dardenne: "Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 12, pp. 5673-81, 1993 (PubMed).

Rozakis-Adcock, Kelly: "Mutational analysis of the ligand-binding domain of the prolactin receptor." in: The Journal of biological chemistry, Vol. 266, Issue 25, pp. 16472-7, 1991 (PubMed).

Dardenne, Kelly, Bach, Savino: "Identification and functional activity of prolactin receptors in thymic epithelial cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 21, pp. 9700-4, 1991 (PubMed).

Okamura, Zachwieja, Raguet, Kelly: "Characterization and applications of monoclonal antibodies to the prolactin receptor." in: Endocrinology, Vol. 124, Issue 5, pp. 2499-508, 1989 (PubMed).

Katoh, Raguet, Zachwieja, Djiane, Kelly: "Hepatic prolactin receptors in the rat: characterization using monoclonal antireceptor antibodies." in: Endocrinology, Vol. 120, Issue 2, pp. 739-49, 1987 (PubMed).

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