Phospholipid Transfer Protein (PLTP) antibody

Details for Product No. ABIN152885
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Antigen
Synonyms zgc:100903, MGC84445, PLTP, hdlcq9, DKFZp469A1437, BPIFE, HDLCQ9, Bpife, OD107
Reactivity
Human, Mouse (Murine)
(46), (21), (13), (12), (12)
Host
Rabbit
(34), (11), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(38), (14), (12), (11), (10), (3), (2), (2), (1), (1)
Pubmed 4 references available
Quantity 0.2 mL
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Catalog No. ABIN152885
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Immunogen A partial peptide of human PLTP.
Purification Whole antisera
Alternative Name PLTP
Background Plasma phospholipid transfer protein (PLTP) plays a central role in regulating plasmaHDL levels and distribution of HDL subpopulations. This regulation is evidenced in vivoby markedly reduced plasma HDL levels in PLTP gene knock-out mice. PLTP alsofacilitates free cholesterol influx into HDL. Alternate Names: Anti-Lipid transfer protein II antibody, Anti-Phospholipid transfer protein antibody. Related Diseases: Atherosclerosis, Insulin resistance, Cancer
Gene Symbol: PLTP
Gene ID 5360, 18830
UniProt P55058
Research Area Cancer, Atherosclerosis, Metabolism
Application Notes This PLTP antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin-embedded sections and Western Blot, where a band is seen at ~55kDa representing PLTP. It does not exhibit neutralizing activity.
Recommended dilutions: Immunocytochemistry/Immunofluorescence 1:50-1:100, Immunohistochemistry 1:200, Western Blot 1:500, Immunohistochemistry-Paraffin 1:200
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Aliquot and store at -20 °C or -80 °C.
Supplier Images
anti-Phospholipid Transfer Protein (PLTP) antibody PLTP detected with 400-106 in human (1) and mouse brain (2) lysates.
General Kawano, Qin, Lin et al.: "Cholesteryl ester transfer protein and phospholipid transfer protein have nonoverlapping functions in vivo." in: The Journal of biological chemistry, Vol. 275, Issue 38, pp. 29477-81, 2000 (PubMed).

Desrumaux, Mak, Boisvert et al.: "Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells." in: Journal of lipid research, Vol. 44, Issue 8, pp. 1453-61, 2003 (PubMed).

Valenta, Ogier, Bradshaw et al.: "Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 26, Issue 7, pp. 1572-8, 2006 (PubMed).

He, Greene, Kinter et al.: "Control of cholesteryl ester transfer protein activity by sequestration of lipid transfer inhibitor protein in an inactive complex." in: Journal of lipid research, Vol. 49, Issue 7, pp. 1529-37, 2008 (PubMed).

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