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Apolipoprotein A-V (APOA5) antibody

Details for Product No. ABIN152905
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Antigen
Synonyms RAP3, Apoav, 1300007O05Rik, APOAV, apo-AV, apoA-V, APOA5, MGC140487, rap3, apoav, apoa-v
Reactivity
Human
(98), (17), (15), (12), (8), (1)
Host
Mouse
(61), (42), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA
(84), (80), (14), (13), (10), (7), (7), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mL
Shipping to United States (Change)
Catalog No. ABIN152905
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Immunogen Ni-NTA purified full-length recombinant human Apolipoprotein A5 expressed in E. Coli strain BL21 (DE3). Immunogen sequence has 83% identity to Bovine, 79% identity to rat and 78% identity to mouse.
Clone 4H8H8E2
Isotype IgG1 kappa
Purification Ascites
Alternative Name Apolipoprotein A V (ApoA V)
Background Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serumtriglyceride concentrations. An ApoA5 mouse knock-out model produced anapproximately four fold increase in serum triglycerides, whereas a knock-in model withhuman ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. Inaddition, peroxisome proliferator-activated receptor-4 (PPAR-alpha) agonists, which areused clinically to lower serum triglyceride concentrations, cause increased ApoA5mRNA expression. Recently, it was demonstrated that ApoA5 ispresent in human serum detected by polyclonal antibodies against both the NH2 andCOOH termini, although at much lower concentration than other apolipoproteins. Alternate Names: anti-ApoA5 antibody, anti-Apolipoprotein A5 antibody, anti-Apo A-V antibody,anti-Apolipoprotein A-V antibody, anti-Apo-A5 antibody, anti-ApoA-V antibody,anti-Apolipoprotein A V antibody. Related Diseases: Coronary Artery Disease, Hypertriglyceridemia
Gene Symbol: APOA5
Gene ID 116519
UniProt Q6Q788
Research Area Metabolism
Application Notes This Apolipoprotein A5 antibody is useful for ELISA.
Recommended dilutions: ELISA 1:100-1:2000
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Aliquot and store at -20 °C or -80 °C.
General Pennacchio, Olivier, Hubacek et al.: "An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing." in: Science (New York, N.Y.), Vol. 294, Issue 5540, pp. 169-73, 2001 (PubMed).

Hosts (61), (42), (4)
Reactivities (98), (17), (15), (12), (8), (1)
Applications (84), (80), (14), (13), (10), (7), (7), (2), (1)
Conjugates (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (11), (11), (3), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN152905
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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