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HDAC3 antibody (Histone Deacetylase 3)

Details for Product anti-HDAC3 Antibody No. ABIN152952, Supplier: Log in to see
Antigen
  • AW537363
  • CG2128
  • dHDAC3
  • DHDAC3
  • Dmel\\CG2128
  • dmHDA402
  • DmHDAC3
  • Dromel_CG2128_FBtr0078767_hdac3_mORF
  • HD3
  • hd3
  • HDAC
  • hdac3
  • Hdac 3
  • HDAC3
  • HDm
  • RPD3
  • RPD3-2
  • rpd3-2
  • XRpd3
  • zgc:55927
Alternatives
anti-Human HDAC3 antibody for Western Blotting
Reactivity
Human, Mouse (Murine), Rat (Rattus)
230
83
74
6
6
4
3
2
1
Host
Rabbit
166
65
Clonality
Polyclonal
Conjugate
This HDAC3 antibody is un-conjugated
7
6
6
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), Microarray (MA), Western Blotting (WB)
195
93
91
66
41
31
25
22
10
4
3
3
2
1
Supplier
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Immunogen Synthetic peptide: C-NEFYDGDHDNDKESDVEI conjugated to KLH, corresponding to amino acids 411-428 of human and chicken HDAC3.
Specificity Anti-Histone Deacetylase 3 specifically recognizes histone deacetylase 3 by immunoblotting and immunoprecipitation (50 kD).
Purification IgG purified
Alternative Name HDAC3 (HDAC3 Antibody Abstract)
Background Gene Symbol: HDAC3
Molecular Weight Theoretical MW: 50 kDa
Gene ID 8841, 15183, 84578
UniProt O15379
Research Area DNA/RNA, Transcription Factors, Wnt, Cancer, Hypertrophy
Pathways Neurotrophin Signaling Pathway
Application Notes Western Blot 1:2000-1:10000, Immunohistochemistry 1:500, Immunoprecipitation 1:2500, Immunohistochemistry-Paraffin 1:500, Microarray
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 12.5 mg/mL
Buffer 0.01M PBS ( pH 7.4)
Buffer contains: 15 mM Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
 image for anti-HDAC3 antibody (Histone Deacetylase 3) (ABIN152952) anti-Histone Deacetylase 3 (HDAC3) antibody
Western Blotting (WB) image for anti-HDAC3 antibody (Histone Deacetylase 3) (ABIN152952) Western Blot: HDAC3 Antibody [ABIN152952] - Cell line lysates (Lanes1. HEK-293T; 2. H...
Immunofluorescence (IF) image for anti-HDAC3 antibody (Histone Deacetylase 3) (ABIN152952) Immunocytochemistry/Immunofluorescence: HDAC3 Antibody [ABIN152952] - HeLa cells were...
Product cited in: Tanaka, Muto, Shima, Katoh, Sax, Tajima, Brydun, Ikura, Yoshizawa, Masai, Hoshikawa, Noda, Nio, Ochiai, Igarashi: "Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3." in: The Journal of biological chemistry, Vol. 291, Issue 12, pp. 6316-30, 2016 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunoprecipitation

Furuya, Guigon, Zhao, Lu, Hanover, Cheng: "Nuclear receptor corepressor is a novel regulator of phosphatidylinositol 3-kinase signaling." in: Molecular and cellular biology, Vol. 27, Issue 17, pp. 6116-26, 2007 (PubMed).

Li, Staver, Curtin, Holms, Frey, Edalji, Smith, Michaelides, Davidsen, Glaser: "Expression and functional characterization of recombinant human HDAC1 and HDAC3." in: Life sciences, Vol. 74, Issue 22, pp. 2693-705, 2004 (PubMed).

Yang, Sharrocks: "SUMO promotes HDAC-mediated transcriptional repression." in: Molecular cell, Vol. 13, Issue 4, pp. 611-7, 2004 (PubMed).

Glaser, Li, Staver, Wei, Albert, Davidsen: "Role of class I and class II histone deacetylases in carcinoma cells using siRNA." in: Biochemical and biophysical research communications, Vol. 310, Issue 2, pp. 529-36, 2003 (PubMed).

Grozinger, Hassig, Schreiber: "Three proteins define a class of human histone deacetylases related to yeast Hda1p." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 9, pp. 4868-73, 1999 (PubMed).

Hassig, Tong, Fleischer, Owa, Grable, Ayer, Schreiber: "A role for histone deacetylase activity in HDAC1-mediated transcriptional repression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 7, pp. 3519-24, 1998 (PubMed).

Background publications Fischle, Emiliani, Hendzel, Nagase, Nomura, Voelter, Verdin: "A new family of human histone deacetylases related to Saccharomyces cerevisiae HDA1p." in: The Journal of biological chemistry, Vol. 274, Issue 17, pp. 11713-20, 1999 (PubMed).

Tong, Hassig, Schnitzler, Kingston, Schreiber: "Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex." in: Nature, Vol. 395, Issue 6705, pp. 917-21, 1998 (PubMed).

Lin, Nagy, Inoue, Shao, Miller, Evans: "Role of the histone deacetylase complex in acute promyelocytic leukaemia." in: Nature, Vol. 391, Issue 6669, pp. 811-4, 1998 (PubMed).

Zhang, LeRoy, Seelig, Lane, Reinberg: "The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities." in: Cell, Vol. 95, Issue 2, pp. 279-89, 1998 (PubMed).

Grunstein: "Histone acetylation in chromatin structure and transcription." in: Nature, Vol. 389, Issue 6649, pp. 349-52, 1997 (PubMed).

Wolffe: "Histone deacetylase: a regulator of transcription." in: Science (New York, N.Y.), Vol. 272, Issue 5260, pp. 371-2, 1996 (PubMed).

Taunton, Hassig, Schreiber: "A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p." in: Science (New York, N.Y.), Vol. 272, Issue 5260, pp. 408-11, 1996 (PubMed).