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Details for Product No. ABIN153017

CAF-1 Subunit antibody

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»Alternatives Fruit Fly (Drosophila melanogaster), Human, Yeast
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN153017
Quantity 50 µL
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Immunogen Recombinant human CAF-1p60.
Clone SS241-68
Isotype IgG1
Specificity Species Reactivity: Human. Localization: Nuclear.
Cross-Reactivity Fruit Fly (Drosophila melanogaster), Human, Yeast
Purification Ascites
Background Chromatin assembly factor 1 (CAF-1) is a member of the histone chaperone family. It isrequired for inheritance of epigenetically determined chromosomal states, and in vitro, itpromotes the assembly of chromatin during DNA replication and DNA repair. CAF-1 isa complex of three subunits, p150, p60, and p48. This complex is localized to thenucleus of human cells.Both the composition and the biochemical activity of CAF-1 are conserved amonghuman, yeast, and Drosophila. Alternate Names: anti-p60 CAF1 antibody, CHAF1B antibody Chromatin assembly factor 1 subunit B antibody, anti-Chromatin assembly factor Iantibody, anti-M phase phosphoprotein 7 antibody, anti-MPHOSPH7 antibody.
Gene ID 8208
UniProt Q13112
Application Notes Suggested working dilutions: immunoprecipitation 0.1-1 ug
Restrictions For Research Use only
Format Liquid
Concentration 31.5 mg/ml
Buffer Ascitic fluid. Preservative: 0.1% sodium azide.
Preservative Sodium azide
Storage -20 °C
Smith, Stillman: "Immunological characterization of chromatin assembly factor I, a human cell factor required for chromatin assembly during DNA replication in vitro." in: The Journal of biological chemistry, Vol. 266, Issue 18, pp. 12041-7, 1991 (PubMed).

Shibahara, Stillman: "Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin." in: Cell, Vol. 96, Issue 4, pp. 575-85, 1999 (PubMed).

Alternatives for antigen "CAF-1 Subunit", type "Antibodies"
Hosts (10), (3)
Reactivities (11), (1), (1)
Applications (11), (10), (5), (3), (1), (1), (1)
Epitopes (1)