PLCB3 antibody (pSer537)

Catalog No. ABIN1531468

Product Details anti-PLCB3 Antibody

Target: PLCB3 (phospholipase C, beta 3 (Phosphatidylinositol-Specific) (PLCB3))

Binding Specificity: AA 503-552, pSer537

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLCB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity:

PLC beta3 (Phospho-Ser537) Antibody detects endogenous levels of PLC beta3 only when phosphorylated at Ser537.

PhosphorylationH:S537 M:S537 R:S535

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PLC beta3 around the phosphorylation site of Ser537.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.591953 (NCBI Gene Symbol: PLCB3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PLCB3

Target: PLCB3 (phospholipase C, beta 3 (Phosphatidylinositol-Specific) (PLCB3))

Alternative Name: PLC Beta3 (PLCB3 Products)

Synonyms: she antibody, Plcbeta3 antibody, wu:fl04b08 antibody, si:zc188c22.1 antibody, si:ch211-188c22.1 antibody, plcb3 antibody, PLCB3 antibody, mKIAA4098 antibody, phospholipase C beta 3 antibody, phospholipase C, beta 3 (phosphatidylinositol-specific) antibody, phospholipase C, beta 3 antibody, PLCB3 antibody, Plcb3 antibody, plcb3 antibody

Background:

Synonyms: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3, Phosphoinositide phospholipase C, Phospholipase C-beta-3, PLC-beta-3, PLCB3

NCBI Gene Symbol: PLCB3

Molecular Weight: 138 kDa

Gene ID: 5331

OMIM: 600230

UniProt: Q01970

Pathways: WNT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, CXCR4-mediated Signaling Events, G-protein mediated Events