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ADAM17 antibody (pThr735)

ADAM17 Reactivity: Human, Rat, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1531481
  • Target See all ADAM17 Antibodies
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    Binding Specificity
    • 16
    • 13
    • 12
    • 8
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 701-750, pThr735
    Reactivity
    • 114
    • 53
    • 51
    • 4
    • 4
    • 4
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 99
    • 13
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 91
    • 25
    Polyclonal
    Conjugate
    • 53
    • 11
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM17 antibody is un-conjugated
    Application
    • 86
    • 52
    • 40
    • 15
    • 14
    • 14
    • 12
    • 11
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
    Specificity

    ADAM 17 (Phospho-Thr735) Antibody detects endogenous levels of ADAM 17 only when phosphorylated at Thr735.

    PhosphorylationH:T735 M:T735 R:T735

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Purity
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human ADAM 17 around the phosphorylation site of Thr735.
    Isotype
    IgG
    Top Product
    Discover our top product ADAM17 Primary Antibody
  • Application Notes
    WB: 1:500~1:1000 ELISA: 1:20000
    Comment

    Unigene-Number: Hs.404914 (NCBI Gene Symbol: ADAM17)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Stable at -20°C for at least 1 year.
    Expiry Date
    12 months
  • Bilousova, Taylor, Emirzian, Gylys, Frautschy, Cole, Teng: "Parallel age-associated changes in brain and plasma neuronal pentraxin receptor levels in a transgenic APP/PS1 rat model of Alzheimer's disease." in: Neurobiology of disease, Vol. 74, pp. 32-40, (2015) (PubMed).

  • Target
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    Alternative Name
    ADAM 17 (ADAM17 Products)
    Synonyms
    ADAM18 antibody, CD156B antibody, CSVP antibody, NISBD antibody, TACE antibody, CD156b antibody, Tace antibody, adam17 antibody, si:dkey-81b15.2 antibody, adam18 antibody, cd156b antibody, csvp antibody, tace antibody, fc20b01 antibody, wu:fc20b01 antibody, zgc:63886 antibody, ADAM metallopeptidase domain 17 antibody, a disintegrin and metallopeptidase domain 17 antibody, ADAM metallopeptidase domain 17b antibody, ADAM metallopeptidase domain 17 L homeolog antibody, ADAM metallopeptidase domain 17a antibody, ADAM17 antibody, Adam17 antibody, adam17b antibody, adam17.L antibody, adam17a antibody
    Background

    Synonyms: ADA17, ADAM 17, CD156b antigen, CSVP, TACE, TNF-alpha convertase, TNF-alpha-converting enzyme, a disintegrin and metalloproteinase domain 17, snake venom-like protease

    NCBI Gene Symbol: ADAM17

    Molecular Weight
    93 kDa
    Gene ID
    6868
    OMIM
    603639
    UniProt
    P78536
    Pathways
    Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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