You are viewing an incomplete version of our website. Please click to reload the website as full version.

FOXP3 antibody (Forkhead Box P3) (C-Term)

Details for Product anti-FOXP3 Antibody No. ABIN153182, Supplier: Log in to see
Antigen
  • foxp3
  • FOXP3
  • AIID
  • DIETER
  • IPEX
  • PIDX
  • XPID
  • JM2
  • scurfin
  • sf
  • RGD1562112
  • forkhead box P3
  • forkhead box P3a
  • transcription factor foxp3
  • FOXP3
  • foxp3a
  • LOC100348270
  • foxp3
  • Foxp3
Epitope
C-Term, both Isoforms
105
53
19
18
14
14
13
13
12
7
6
6
6
6
6
5
4
4
4
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Reactivity
Human
417
274
44
44
12
8
8
5
4
2
2
1
1
1
Host
Goat
255
187
37
31
Clonality
Polyclonal
Conjugate
This FOXP3 antibody is un-conjugated
37
30
21
19
19
18
18
10
9
9
9
7
6
6
5
5
3
3
3
3
2
Application
Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
292
204
179
101
86
77
74
58
29
17
5
5
4
4
2
2
2
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen Peptide with sequence SQRPSRCSNPTPGP corresponding to C-Terminus according to NP_054728.2, NP_001107849.1.
Specificity This antibody is expected to recognize both reported isoforms (NP_054728.2 and NP_001107849.1)
Cross-Reactivity (Details) Predicted cross-reactivity based on sequence identity: Dog, Pig
Purification Immunogen affinity purified
Alternative Name FoxP3 (FOXP3 Antibody Abstract)
Background Gene Symbol: FOXP3
Gene ID 50943
NCBI Accession NP_054728
Application Notes Western Blot 1:1000, Chromatin Immunoprecipitation 1:200, Immunohistochemistry 0.3 - 1 μg/mL, Immunocytochemistry/Immunofluorescence 2 - 4 μg/mL, Immunohistochemistry-Paraffin 0.3 - 1 μg/mL, Peptide ELISA Detection limit 1:8000ChIP successful usage on activated human T cells is reported in scientific literature (PMID: 19777054). ICC usage on CD25-sorted (Treg) human blood cells with nuclear speckled staining, overnight staining. WB successful usage on human T regulatory cells is reported in scientific literature (PMID: 15374887). IHC-P: Human tonsil with stained nuclei of some cells in the interfollicular area.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 0.5 mg/mL Tris ( pH 7.3) and 0.5 % BSA
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Immunohistochemistry (IHC) image for anti-FOXP3 antibody (Forkhead Box P3) (C-Term) (ABIN153182) anti-Forkhead Box P3 (FOXP3) (C-Term), (both Isoforms) antibody
Immunohistochemistry (IHC) image for anti-FOXP3 antibody (Forkhead Box P3) (C-Term) (ABIN153182) anti-Forkhead Box P3 (FOXP3) (C-Term), (both Isoforms) antibody (Image 2)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FOXP3 antibody (Forkhead Box P3) (C-Term) (ABIN153182) Immunohistochemistry-Paraffin: FoxP3 Antibody [ABIN153182] - Staining of paraffin emb...
Immunohistochemistry (IHC) image for anti-FOXP3 antibody (Forkhead Box P3) (C-Term) (ABIN153182) Immunohistochemistry: FoxP3 Antibody [ABIN153182] - Staining of CD25-sorted (Treg) hu...
Product cited in: Petrilli, Lorenzi, Paracchini, Ubiali, Schumacher, Cabassa, Facchetti: "Epstein-Barr virus-associated adrenal smooth muscle tumors and disseminated diffuse large B-cell lymphoma in a child with common variable immunodeficiency: a case report and review of the literature." in: International journal of surgical pathology, Vol. 22, Issue 8, pp. 712-21, 2014 (PubMed). (Sample species: Human). Further details: Immunohistochemistry

Turnquist, Zhao, Rosborough, Liu, Castellaneta, Isse, Wang, Lang, Stolz, Zheng, Demetris, Liew, Wood, Thomson: "IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 9, pp. 4598-610, 2011 (PubMed).

Shen, Shin, Strle, McHugh, Li, Glickstein, Drouin, Steere: "Treg cell numbers and function in patients with antibiotic-refractory or antibiotic-responsive Lyme arthritis." in: Arthritis and rheumatism, Vol. 62, Issue 7, pp. 2127-37, 2010 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence,Immunohistochemistry

Stahl, Fauti, Ullrich, Bopp, Kubach, Rust, Labhart, Alexiadis, Becker, Hafner, Weith, Lenter, Jonuleit, Schmitt, Mennerich: "miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression." in: PLoS ONE, Vol. 4, Issue 9, pp. e7158, 2009 (PubMed).

Banham, Brown, Lyne, Schulze, Hallermann: "Is FOXP3 expressed in cutaneous T-cell lymphomas?" in: European journal of haematology, Vol. 80, Issue 1, pp. 90-1, 2008 (PubMed).

Radulovic, Jacobson, Durham, Nouri-Aria: "Grass pollen immunotherapy induces Foxp3-expressing CD4+ CD25+ cells in the nasal mucosa." in: The Journal of allergy and clinical immunology, Vol. 121, Issue 6, pp. 1467-72, 1472.e1, 2008 (PubMed).

Mansour, Homs, Desvaux, Badoual, Dahan, Matignon, Audard, Lang, Grimbert: "Intragraft levels of Foxp3 mRNA predict progression in renal transplants with borderline change." in: Journal of the American Society of Nephrology : JASN, Vol. 19, Issue 12, pp. 2277-81, 2008 (PubMed).

Ward, Hall, Cairns, Leggat, Urbaniak, Vickers, Barker: "Clonal regulatory T cells specific for a red blood cell autoantigen in human autoimmune hemolytic anemia." in: Blood, Vol. 111, Issue 2, pp. 680-7, 2008 (PubMed).

Schmidt-Lucke, Aicher, Romagnani, Gareis, Romagnani, Zeiher, Dimmeler: "Specific recruitment of CD4+CD25++ regulatory T cells into the allograft in heart transplant recipients." in: American journal of physiology. Heart and circulatory physiology, Vol. 292, Issue 5, pp. H2425-31, 2007 (PubMed).

Kiniwa, Miyahara, Wang, Peng, Peng, Wheeler, Thompson, Old, Wang: "CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 23, pp. 6947-58, 2007 (PubMed).

Nakamura, Shima, Saeki, Hidaka, Nakashima, Takikawa, Saito: "Expression of indoleamine 2, 3-dioxygenase and the recruitment of Foxp3-expressing regulatory T cells in the development and progression of uterine cervical cancer." in: Cancer science, Vol. 98, Issue 6, pp. 874-81, 2007 (PubMed).

Nilsson, Boasso, Velilla, Zhang, Vaccari, Franchini, Shearer, Andersson, Chougnet: "HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS." in: Blood, Vol. 108, Issue 12, pp. 3808-17, 2006 (PubMed).

Andersson, Boasso, Nilsson, Zhang, Shire, Lindback, Shearer, Chougnet: "The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 6, pp. 3143-7, 2005 (PubMed).

Karube, Ohshima, Tsuchiya, Yamaguchi, Kawano, Suzumiya, Utsunomiya, Harada, Kikuchi: "Expression of FoxP3, a key molecule in CD4CD25 regulatory T cells, in adult T-cell leukaemia/lymphoma cells." in: British journal of haematology, Vol. 126, Issue 1, pp. 81-4, 2004 (PubMed).

Chatila, Blaeser, Ho, Lederman, Voulgaropoulos, Helms, Bowcock: "JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome." in: The Journal of clinical investigation, Vol. 106, Issue 12, pp. R75-81, 2001 (PubMed).