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FOXP3 antibody (Forkhead Box P3) (C-Term)

Details for Product anti-FOXP3 Antibody No. ABIN153182, Supplier: Log in to see
Antigen
  • AIID
  • DIETER
  • foxp3
  • FOXP3
  • IPEX
  • JM2
  • PIDX
  • RGD1562112
  • scurfin
  • sf
  • XPID
Epitope
C-Term, both Isoforms
89
22
14
13
13
13
11
7
6
6
6
6
6
5
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
Reactivity
Human
323
183
56
22
22
21
16
12
9
8
2
2
1
1
Host
Goat
204
130
66
32
Clonality
Polyclonal
Conjugate
This FOXP3 antibody is un-conjugated
36
30
22
19
15
13
11
10
6
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
Application
Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
239
167
140
85
38
31
29
28
18
17
15
6
5
4
2
2
2
1
Supplier
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Immunogen Peptide with sequence SQRPSRCSNPTPGP corresponding to C-Terminus according to NP_054728.2, NP_001107849.1.
Specificity This antibody is expected to recognize both reported isoforms (NP_054728.2 and NP_001107849.1)
Cross-Reactivity (Details) Predicted cross-reactivity based on sequence identity: Dog, Pig
Purification Immunogen affinity purified
Alternative Name FoxP3 (FOXP3 Antibody Abstract)
Background Gene Symbol: FOXP3
NCBI Accession NP_054728
Application Notes Western Blot 1:1000, Chromatin Immunoprecipitation 1:200, Immunohistochemistry 0.3 - 1 μg/mL, Immunocytochemistry/Immunofluorescence 2 - 4 μg/mL, Immunohistochemistry-Paraffin 0.3 - 1 μg/mL, Peptide ELISA Detection limit 1:8000
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris saline, pH 7.3 with 0.5 % BSA.
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Immunohistochemistry (IHC) image for anti-FOXP3 antibody (Forkhead Box P3) (C-Term) (ABIN153182) anti-Forkhead Box P3 (FOXP3) (C-Term), (both Isoforms) antibody
Immunohistochemistry (IHC) image for anti-FOXP3 antibody (Forkhead Box P3) (C-Term) (ABIN153182) anti-Forkhead Box P3 (FOXP3) (C-Term), (both Isoforms) antibody (Image 2)
Product cited in: Schmidt-Lucke, Aicher, Romagnani, Gareis, Romagnani, Zeiher, Dimmeler: "Specific recruitment of CD4+CD25++ regulatory T cells into the allograft in heart transplant recipients." in: American journal of physiology. Heart and circulatory physiology, Vol. 292, Issue 5, pp. H2425-31, 2007

Kiniwa, Miyahara, Wang, Peng, Peng, Wheeler, Thompson, Old, Wang: "CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 23, pp. 6947-58, 2007

Nilsson, Boasso, Velilla, Zhang, Vaccari, Franchini, Shearer, Andersson, Chougnet: "HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS." in: Blood, Vol. 108, Issue 12, pp. 3808-17, 2006

Andersson, Boasso, Nilsson, Zhang, Shire, Lindback, Shearer, Chougnet: "The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 6, pp. 3143-7, 2005

Karube, Ohshima, Tsuchiya, Yamaguchi, Kawano, Suzumiya, Utsunomiya, Harada, Kikuchi: "Expression of FoxP3, a key molecule in CD4CD25 regulatory T cells, in adult T-cell leukaemia/lymphoma cells." in: British journal of haematology, Vol. 126, Issue 1, pp. 81-4, 2004

Background publications Chatila, Blaeser, Ho, Lederman, Voulgaropoulos, Helms, Bowcock: "JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome." in: The Journal of clinical investigation, Vol. 106, Issue 12, pp. R75-81, 2001