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Merlin antibody (pSer10)

NF2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1532019
  • Target See all Merlin (NF2) Antibodies
    Merlin (NF2) (Neurofibromin 2 (NF2))
    Binding Specificity
    • 28
    • 15
    • 9
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50, pSer10
    Reactivity
    • 76
    • 64
    • 52
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 87
    • 4
    • 1
    Rabbit
    Clonality
    • 89
    • 3
    Polyclonal
    Conjugate
    • 46
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This Merlin antibody is un-conjugated
    Application
    • 70
    • 29
    • 27
    • 26
    • 18
    • 17
    • 11
    • 11
    • 6
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity

    Merlin (Phospho-Ser10) Antibody detects endogenous levels of Merlin only when phosphorylated at Ser10.

    PhosphorylationH:S10 M:S10 R:S6

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Purity
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human Merlin around the phosphorylation site of Ser10.
    Isotype
    IgG
    Top Product
    Discover our top product NF2 Primary Antibody
  • Application Notes
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000
    Comment

    Unigene-Number: Hs.187898 (NCBI Gene Symbol: NF2)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Stable at -20°C for at least 1 year.
    Expiry Date
    12 months
  • Yu, Zeidel, Hill: "Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast." in: PLoS ONE, Vol. 7, Issue 11, pp. e48897, (2012) (PubMed).

  • Target
    Merlin (NF2) (Neurofibromin 2 (NF2))
    Alternative Name
    Merlin (NF2 Products)
    Background

    Synonyms: MERL, moesin-ezrin-radizin-like protein, neurofibromatosis type 2 gene, neurofibromatosis-2, Neurofibromin 2, NF-2, NF2, SCH, Schwannomerlin, schwannomerlin, Schwannomin

    NCBI Gene Symbol: NF2

    Molecular Weight
    69 kDa
    Gene ID
    4771
    OMIM
    101000
    UniProt
    P35240
    Pathways
    Cell-Cell Junction Organization
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