MAP3K8 antibody (pSer400)

Catalog No. ABIN1532057

Product Details anti-MAP3K8 Antibody

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Binding Specificity: AA 366-415, pSer400

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K8 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Specificity:

MAP3K8 (Phospho-Ser400) Antibody detects endogenous levels of MAP3K8 only when phosphorylated at Ser400.

PhosphorylationH:S400 M:S400 R:S400

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MAP3K8 around the phosphorylation site of Ser400.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.432453 (NCBI Gene Symbol: MAP3K8)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for MAP3K8

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Alternative Name: MAP3K8 (MAP3K8 Products)

Synonyms: MAP3K8 antibody, COT antibody, EST antibody, ESTF antibody, MEKK8 antibody, TPL2 antibody, Tpl-2 antibody, c-COT antibody, Cot antibody, Cot/Tpl2 antibody, Est antibody, Estf antibody, Tpl2 antibody, D17TPL2 antibody, mitogen-activated protein kinase kinase kinase 8 antibody, MAP3K8 antibody, map3k8 antibody, Map3k8 antibody

Background:

Synonyms: COT proto-oncogene serine/threonine-protein kinase, C-COT, Cancer Osaka thyroid oncogene, Tumor progression locus 2, TPL-2

NCBI Gene Symbol: MAP3K8

Molecular Weight: 52 kDa

Gene ID: 1326

OMIM: 191195

UniProt: P41279

Pathways: PI3K-Akt Signaling, TCR Signaling