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FRS2 antibody (pTyr436)

FRS2 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1532103
  • Target See all FRS2 Antibodies
    FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
    Binding Specificity
    • 15
    • 14
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 402-451, pTyr436
    Reactivity
    • 63
    • 25
    • 19
    • 2
    Human, Mouse
    Host
    • 73
    • 6
    • 2
    • 1
    Rabbit
    Clonality
    • 78
    • 4
    Polyclonal
    Conjugate
    • 39
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FRS2 antibody is un-conjugated
    Application
    • 59
    • 41
    • 14
    • 14
    • 12
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity

    FRS2 (Phospho-Tyr436) Antibody detects endogenous levels of FRS2 only when phosphorylated at Tyr436.

    PhosphorylationH:Y436 M:Y436

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Purity
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human FRS2 around the phosphorylation site of Tyr436.
    Isotype
    IgG
    Top Product
    Discover our top product FRS2 Primary Antibody
  • Application Notes
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000
    Comment

    Unigene-Number: Hs.593446 (NCBI Gene Symbol: FRS2)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Stable at -20°C for at least 1 year.
    Expiry Date
    12 months
  • Sun, Zou, Yang, Morita, Gong, Shiba, Akagawa, Yuan: "Inorganic polyphosphates stimulate FGF23 expression through the FGFR pathway." in: Biochemical and biophysical research communications, Vol. 428, Issue 2, pp. 298-302, (2012) (PubMed).

  • Target
    FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
    Alternative Name
    FRS2 (FRS2 Products)
    Synonyms
    frs2 antibody, wu:fd21h10 antibody, zgc:91973 antibody, FRS2A antibody, FRS2alpha antibody, SNT antibody, SNT-1 antibody, SNT1 antibody, 4732458E18 antibody, C330018A15Rik antibody, Frs2alpha antibody, fibroblast growth factor receptor substrate 2 antibody, fibroblast growth factor receptor substrate 2b antibody, FRS2 antibody, frs2b antibody, Frs2 antibody
    Background

    Synonyms: FGFR signalling adaptor, FGFR signalling adaptor SNT-1, SNT-1, SNT2, SUC1-associated neurotrophic factor target, Suc1-associated neurotrophic factor target

    NCBI Gene Symbol: FRS2

    Molecular Weight
    57 kDa
    Gene ID
    10818
    OMIM
    607743
    UniProt
    Q8WU20
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2
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