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GRB2 antibody (pSer159)

GRB2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1532105
  • Target See all GRB2 Antibodies
    GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
    Binding Specificity
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 125-174, pSer159
    Reactivity
    • 62
    • 30
    • 29
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 50
    • 9
    • 3
    Rabbit
    Clonality
    • 52
    • 9
    • 1
    Polyclonal
    Conjugate
    • 43
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRB2 antibody is un-conjugated
    Application
    • 47
    • 32
    • 16
    • 12
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity

    GRB2 (Phospho-Ser159) Antibody detects endogenous levels of GRB2 only when phosphorylated at Ser159.

    PhosphorylationH:S159 M:S160 R:S160

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Purity
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human GRB2 around the phosphorylation site of Ser159.
    Isotype
    IgG
    Top Product
    Discover our top product GRB2 Primary Antibody
  • Application Notes
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000
    Comment

    Unigene-Number: Hs.429434 (NCBI Gene Symbol: GAB2)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Stable at -20°C for at least 1 year.
    Expiry Date
    12 months
  • Target
    GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
    Alternative Name
    GRB2 (GRB2 Products)
    Background

    Synonyms: GRB2-associated-binding protein 2, Growth factor receptor bound protein 2-associated protein 2, GRB2-associated binder 2, pp100, KIAA0571

    NCBI Gene Symbol: GAB2

    Molecular Weight
    74 kDa
    Gene ID
    9846
    OMIM
    606203
    UniProt
    Q9UQC2
    Pathways
    RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
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