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Presenilin 1 antibody (pSer357)

PSEN1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1532166
  • Target See all Presenilin 1 (PSEN1) Antibodies
    Presenilin 1 (PSEN1)
    Binding Specificity
    • 31
    • 15
    • 15
    • 13
    • 11
    • 11
    • 8
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 323-372, pSer357
    Reactivity
    • 122
    • 100
    • 65
    • 9
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 110
    • 36
    • 2
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 144
    • 8
    Polyclonal
    Conjugate
    • 48
    • 12
    • 12
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    This Presenilin 1 antibody is un-conjugated
    Application
    • 121
    • 55
    • 54
    • 52
    • 52
    • 18
    • 15
    • 13
    • 11
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificity

    PSEN1 (Phospho-Ser357) Antibody detects endogenous levels of PSEN1 only when phosphorylated at Ser357.

    PhosphorylationH:S357 M:S357 R:S358

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Purity
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human PSEN1 around the phosphorylation site of Ser357.
    Isotype
    IgG
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  • Application Notes
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000
    Comment

    Unigene-Number: Hs.3260 (NCBI Gene Symbol: PSEN1)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Stable at -20°C for at least 1 year.
    Expiry Date
    12 months
  • Target
    Presenilin 1 (PSEN1)
    Alternative Name
    PSEN1 (PSEN1 Products)
    Synonyms
    pre1 antibody, psen antibody, zfPS1 antibody, zf-PS1 antibody, ad3 antibody, fad antibody, ps1 antibody, s182 antibody, X-PS-beta antibody, X-PS-alpha antibody, AD3 antibody, FAD antibody, PS-1 antibody, PS1 antibody, S182 antibody, Ad3h antibody, presenilin 1 antibody, presenilin 1 L homeolog antibody, psen1 antibody, PSEN1 antibody, Psen1 antibody, psen1.L antibody
    Background

    Synonyms: AD3, AD3H, presenilin 1, PS-1, PS1, PSN1, PSNL1, S182 protein

    NCBI Gene Symbol: PSEN1

    Molecular Weight
    52 kDa
    Gene ID
    5663
    OMIM
    104311
    UniProt
    P49768
    Pathways
    Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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