Presenilin 1 antibody (pSer357)
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- Target See all Presenilin 1 (PSEN1) Antibodies
- Presenilin 1 (PSEN1)
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Binding Specificity
- AA 323-372, pSer357
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Presenilin 1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificity
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PSEN1 (Phospho-Ser357) Antibody detects endogenous levels of PSEN1 only when phosphorylated at Ser357.
PhosphorylationH:S357 M:S357 R:S358
- Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
- Purity
- > 95 %
- Immunogen
- The antiserum was produced against synthesized peptide derived from human PSEN1 around the phosphorylation site of Ser357.
- Isotype
- IgG
- Top Product
- Discover our top product PSEN1 Primary Antibody
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- Application Notes
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000
- Comment
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Unigene-Number: Hs.3260 (NCBI Gene Symbol: PSEN1)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable at -20°C for at least 1 year.
- Expiry Date
- 12 months
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- Target
- Presenilin 1 (PSEN1)
- Alternative Name
- PSEN1 (PSEN1 Products)
- Synonyms
- pre1 antibody, psen antibody, zfPS1 antibody, zf-PS1 antibody, ad3 antibody, fad antibody, ps1 antibody, s182 antibody, X-PS-beta antibody, X-PS-alpha antibody, AD3 antibody, FAD antibody, PS-1 antibody, PS1 antibody, S182 antibody, Ad3h antibody, presenilin 1 antibody, presenilin 1 L homeolog antibody, psen1 antibody, PSEN1 antibody, Psen1 antibody, psen1.L antibody
- Background
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Synonyms: AD3, AD3H, presenilin 1, PS-1, PS1, PSN1, PSNL1, S182 protein
NCBI Gene Symbol: PSEN1
- Molecular Weight
- 52 kDa
- Gene ID
- 5663
- OMIM
- 104311
- UniProt
- P49768
- Pathways
- Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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