WNK Lysine Deficient Protein Kinase 4 (WNK4) antibody

Details for Product No. ABIN153223
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Antigen
Synonyms 2010002J11Rik, Pha2b, Prkwnk4, Ac2-059, PHA2B, PRKWNK4, WNK4
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(22), (19), (18)
Host
Rabbit
(24), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(15), (10), (7), (4), (1)
Pubmed 3 references available
Catalog no. ABIN153223
Quantity 0.1 mL
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Immunogen A synthetic peptide sequence made to a region of the human protein between residues200-300.
Specificity ABIN153223 is specific for WNK4 protein. Species Reactivity: ABIN153223 can be used to detect mouse and human (very weakly) WNK4 protein.
Alternative Name WNK4
Background WNK kinases play an important role in hypertension. WNK4 localizes to both tightjunctions and to a segment of kidney involved in salt, potassium, and pH homeostasis,the distal nephron.
Gene ID 65266
UniProt Q96J92
Research Area Signaling
Application Notes Suggested working dilutions: Western Blot 2 ug/ml. Positive Controls: Mouse kidney lysate
Restrictions For Research Use only
Format Liquid
Concentration 0.92 mg/ml
Buffer 0.1 ml of affinity purified antisera.
Storage -20 °C
Supplier Images
anti-WNK Lysine Deficient Protein Kinase 4 (WNK4) antibody Detection of WNK4 in mouse kidney lysate using ABIN153223.
General Wilson, Disse-Nicodème, Choate et al.: "Human hypertension caused by mutations in WNK kinases." in: Science (New York, N.Y.), Vol. 293, Issue 5532, pp. 1107-12, 2001 (PubMed).

Kahle, Gimenez, Hassan et al.: "WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 7, pp. 2064-9, 2004 (PubMed).

Song, Hu, Riazi et al.: "Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats." in: American journal of physiology. Renal physiology, Vol. 290, Issue 5, pp. F1055-64, 2006 (PubMed).

Hosts (24), (1)
Reactivities (22), (19), (18)
Applications (15), (10), (7), (4), (1)
Conjugates (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (1), (1), (1)
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