Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Add to Basket
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN153387

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms
G3PD, GAPD, Gapd, cb609, gapd, mg:bb02e05, wu:fb33a10, wu:ft80f05, KNC-NDS6, G3PDH, CG8893, Dmel\\CG8893, GA3PDH, GADPH, GAP, GAPDH, GAPDH II, GAPDH2, Gapdh, Gapdh-2, Gapdh13F, BEST:GH12586, CG12055,  ... show more
Reactivity
»Alternatives Dog (Canine), Chicken, Fish, Human, Mouse (Murine), Rabbit, Rat (Rattus), Xenopus laevis
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
Pubmed 10 references available
Catalog no. ABIN153387
Quantity 0.1 mg
Price
Contact our Customer Service for availability and price in your country.
Shipping to
Immunogen Rabbit muscle GAPDH.
Clone 6C5
Isotype IgG1
Specificity GAPDH is a 146 kDa tetramer composed of four 30-40 kDa subunits. There is nocross-reaction with GAPDH from yeast. Species Reactivity: Cross-reacts with Human, Chicken, Dog, Fish, Mouse, Rabbit, Rat and Xenopus laevis.Does not cross-react with Cow, Goat, or s. Cerevisiae. Not yet tested in other species. Localization: Cytoplasmic.
Cross-Reactivity Dog (Canine), Chicken, Fish, Human, Mouse (Murine), Rabbit, Rat (Rattus), Xenopus laevis
Purification Purified
Alternative Name GAPDH
Background Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the keyenzymes involved in glycolysis. Besides its functioning as a glycolytic enzyme incytoplasm, recent evidence suggests that mammalian GAPDH is also involved in agreat number of intracellular proceses such as membrane fusion, microtubule bundling,phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair.Recently data has implicated GAPDH in different pathologies including prostate cancerprogression, programmed neuronal cell death, age-related neuronal diseases, such asAlzheimer',s and Huntington',s disease. Some physiological factors, such ashypoxia and diabetes, increase GAPDH expression in certain cell types. Alternate Names: anti-GAPDH antibody, anti-glyceraldehyde-3-phosphate dehydrogenase antibody,anti-HGNC:4141 antibody, anti-G3PD antibody, anti-GAPD antibody, anti-MGC88685antibody.
Gene ID 2597, 14433, 24383
Research Area Cancer, Metabolism, Alzheimer's Disease, Enzymes
Application Notes Suggested working dilutions: Western Blot 1/500,Immunohistochemistry-Frozen
Restrictions For Research Use only
Concentration 2.0 mg/ml
Buffer PBS. pH 7.4. Preservative: Sodium Azide.
Preservative Sodium azide
Storage 4 °C
Kapadia, Brideau-Andersen, Chisari: "Interference of hepatitis C virus RNA replication by short interfering RNAs." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 4, pp. 2014-8, 2003 (PubMed).

Ikeda, Caldwell, Longnecker et al.: "Itchy, a Nedd4 ubiquitin ligase, downregulates latent membrane protein 2A activity in B-cell signaling." in: Journal of virology, Vol. 77, Issue 9, pp. 5529-34, 2003 (PubMed).

Irvin, Wood, Wang et al.: "TEL, a putative tumor suppressor, induces apoptosis and represses transcription of Bcl-XL." in: The Journal of biological chemistry, Vol. 278, Issue 47, pp. 46378-86, 2003 (PubMed).

Baskurt, Yalcin, Ozdem et al.: "Modulation of endothelial nitric oxide synthase expression by red blood cell aggregation." in: American journal of physiology. Heart and circulatory physiology, Vol. 286, Issue 1, pp. H222-9, 2003 (PubMed).

Sumner, Huynh, Markowitz et al.: "Valproic acid increases SMN levels in spinal muscular atrophy patient cells." in: Annals of neurology, Vol. 54, Issue 5, pp. 647-54, 2003 (PubMed).

Cuezva, Chen, Alonso et al.: "The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis." in: Carcinogenesis, Vol. 25, Issue 7, pp. 1157-63, 2004 (PubMed).

Akassoglou, Malester, Xu et al.: "Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 14, pp. 5075-80, 2004 (PubMed).

He, Jazdzewski, Li et al.: "The role of microRNA genes in papillary thyroid carcinoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 52, pp. 19075-80, 2005 (PubMed).

Arthur, Akassoglou, Insel: "P2Y2 receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 52, pp. 19138-43, 2005 (PubMed).

Kanadia, Shin, Yuan et al.: "Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 31, pp. 11748-53, 2006 (PubMed).

Alternatives for antigen "Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)", type "Antibodies"
Hosts (250), (199), (37), (22), (20)
Reactivities (398), (244), (211), (107), (59), (39), (37), (35), (26), (26), (24), (20), (16), (13), (13), (11), (10), (9), (7), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (446), (237), (139), (81), (78), (60), (50), (37), (16), (13), (7), (6), (5), (5), (4), (2), (2), (1), (1)
Conjugates (30), (24), (7), (7), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (2), (2), (1), (1)
Epitopes (82), (34), (11), (10), (6), (6), (5), (5), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1)
Beacon