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ACTG2 antibody (Actin, gamma 2, Smooth Muscle, Enteric) (N-Term)

Details for Product anti-ACTG2 Antibody No. ABIN153416, Supplier: Log in to see
Antigen
  • ACTG2
  • ACTGE
  • SMGA
  • ACT
  • ACTA3
  • ACTE
  • ACTL3
  • ACTSG
  • Act-4
  • Act4
  • GAMMA-ACTIN
  • actin, gamma 2, smooth muscle, enteric
  • actin, alpha 2, smooth muscle, aorta
  • ACTG2
  • ACTA2
  • Actg2
Epitope
N-Term
94
14
14
5
3
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
176
127
79
52
52
49
47
46
45
45
45
45
44
27
22
1
1
1
1
Host
Rabbit
118
56
2
Clonality
Polyclonal
Conjugate
This ACTG2 antibody is un-conjugated
7
6
6
6
5
5
5
5
5
5
4
4
4
4
4
4
4
2
2
2
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
115
100
71
64
62
51
46
16
12
8
4
3
3
2
2
1
1
Options
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Immunogen Synthetic peptide corresponding to N-terminus of human alpha smooth muscle isoform of actin.
Specificity This alpha-sma antibody stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also stained. It reacts with tumors arising from smooth muscles and myoepithelial cells.
Purification Immunogen affinity purified
Alternative Name alpha-Smooth Muscle Actin (ACTG2 Antibody Abstract)
Background Gene Symbol: ACTA2
Molecular Weight Theoretical MW: 42 kDa
Gene ID 59
UniProt P62736
Application Notes Western Blot 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:100-1:400, Immunohistochemistry-FrozenUse in Immunohistochemistry-Frozen reported in scientific literature (PMID 25783396). Use in Western Blot reported in scientific literature (PMID 27029074). Use in ICC/IF reported in scientific literature (PMID 26417067). The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS ( pH 7.6) and 1.0 % BSA
Buffer contains: 0.1 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 4°C. Do not freeze.
Supplier Images
Immunohistochemistry (IHC) image for anti-ACTG2 antibody (Actin, gamma 2, Smooth Muscle, Enteric) (N-Term) (ABIN153416) Formalin-fixed, paraffin-embedded Human Leiomyoma stained with ABIN153416
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ACTG2 antibody (Actin, gamma 2, Smooth Muscle, Enteric) (N-Term) (ABIN153416) Immunohistochemistry-Paraffin: alpha-Smooth Muscle Actin Antibody [ABIN153416] - Huma...
Product cited in: Ben Shoham, Rot, Stern, Krief, Akiva, Dadosh, Sabany, Lu, Kadler, Zelzer: "Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology." in: Development (Cambridge, England), Vol. 143, Issue 21, pp. 3933-3943, 2016 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunocytochemistry,Immunofluorescence

Robbins, Mateson, Khandha, Pugarelli, Buchanan, Akins, Barthold: "Fetal Rat Gubernaculum Mesenchymal Cells Adopt Myogenic and Myofibroblast-Like Phenotypes." in: The Journal of urology, Vol. 196, Issue 1, pp. 270-8, 2016 (PubMed). Method employed by authors: Western Blotting (WB)

Kadam, Chuan: "Erratum to: Rectocutaneous fistula with transmigration of the suture: a rare delayed complication of vault fixation with the sacrospinous ligament." in: International urogynecology journal, Vol. 27, Issue 3, pp. 505, 2016 (PubMed).

Conte, Fagone, Gili, Fruciano, Iemmolo, Pistorio, Impellizzeri, Cordaro, Cuzzocrea, Vancheri: "Preventive and therapeutic effects of thymosin β4 N-terminal fragment Ac-SDKP in the bleomycin model of pulmonary fibrosis." in: Oncotarget, Vol. 7, Issue 23, pp. 33841-54, 2016 (PubMed). (Sample species: Human).

Tate, Mc Entire, Pallini, Vakana, Wyss, Blosser, Ricci-Vitiani, DAlessandris, Morgante, Giannetti, Larocca, Todaro, Benfante, Colorito, Stassi, De Maria, Rowlinson, Stancato: "A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology." in: PLoS ONE, Vol. 10, Issue 4, pp. e0125697, 2015 (PubMed). (Sample species: Human). Further details: Immunohistochemistry (Free Floating)

Inada, Saitoh, Watanabe, Aoki, Miura, Ohtsuka, Murakami, Sawami, Yamasaki, Sato: "PiggyBac transposon-mediated gene delivery efficiently generates stable transfectants derived from cultured primary human deciduous tooth dental pulp cells (HDDPCs) and HDDPC-derived iPS cells." in: International journal of oral science, Vol. 7, Issue 3, pp. 144-54, 2015 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Marchi, Corricelli, Trapani, Bravi, Pittaro, Delle Monache, Ferroni, Patergnani, Missiroli, Goitre, Trabalzini, Rimessi, Giorgi, Zavan, Cassoni, Dejana, Retta, Pinton: "Defective autophagy is a key feature of cerebral cavernous malformations." in: EMBO molecular medicine, Vol. 7, Issue 11, pp. 1403-17, 2015 (PubMed). Further details: Immunocytochemistry,Immunofluorescence

Ramani, Donoyan, Tomasi, Park: "Role of methionine adenosyltransferase α2 and β phosphorylation and stabilization in human hepatic stellate cell trans-differentiation." in: Journal of cellular physiology, Vol. 230, Issue 5, pp. 1075-85, 2015 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Western Blotting,Immunofluorescence

Coyle, ODonnell, Puri: "Altered distribution of small-conductance calcium-activated potassium channel SK3 in Hirschsprung's disease." in: Journal of pediatric surgery, Vol. 50, Issue 10, pp. 1659-64, 2015 (PubMed). (Sample species: Human). Further details: Immunohistochemistry (Frozen Sections)

Kwon, Nabinger, Vega, Sahu, Alluri, Abdul-Sater, Yu, Gore, Nalepa, Saxena, Korc, Kota: "Pathophysiological role of microRNA-29 in pancreatic cancer stroma." in: Scientific reports, Vol. 5, pp. 11450, 2015 (PubMed). Further details: Immunocytochemistry,Immunofluorescence

Ge, Pettan-Brewer, Morton, Carter, Fatemi, Rabinovitch, Ladiges: "Mitochondrial catalase suppresses naturally occurring lung cancer in old mice." in: Pathobiology of aging & age related diseases, Vol. 5, pp. 28776, 2015 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunohistochemistry

Stawski, Han, Bujor, Trojanowska: "Angiotensin II induces skin fibrosis: a novel mouse model of dermal fibrosis." in: Arthritis research & therapy, Vol. 14, Issue 4, pp. R194, 2014 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunocytochemistry,Immunofluorescence,Immunohistochemistry

Court, Amoyel, Hackman, Lee, Xu, Miller, Bar-Sagi, Bach, Bergö, Philips: "Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression." in: The Journal of clinical investigation, Vol. 123, Issue 11, pp. 4681-94, 2014 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Takamiya, Fukami, Yamagishi, Kaida, Nakayama, Obara, Iwatani, Ando, Koike, Matsui, Nishino, Ueda, Cooper, Okuda: "Experimental diabetic nephropathy is accelerated in matrix metalloproteinase-2 knockout mice." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 28, Issue 1, pp. 55-62, 2013 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Danielson, Park, Rotllan, Chamorro-Jorganes, Guijarro, Fernandez-Hernando, Fishman, Phoon, Hernando: "Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 4, pp. 1460-7, 2013 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunohistochemistry

Takamura, Nakanuma, Hayashi, Tajima, Kakinoki, Sakai, Makino, Nakagawara, Miyashita, Okamoto, Nakamura, Oyama, Inokuchi, Ninomiya, Kitagawa, Fushida, Fujimura, Ohnishi, Kayahara, Tani, Arai et al.: "Evaluation of eligibility criteria in living donor liver transplantation for hepatocellular carcinoma by α-SMA-positive cancer-associated fibroblasts. ..." in: Oncology reports, Vol. 30, Issue 4, pp. 1561-74, 2013 (PubMed). (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Moriondo, Solari, Marcozzi, Negrini: "Spontaneous activity in peripheral diaphragmatic lymphatic loops." in: American journal of physiology. Heart and circulatory physiology, Vol. 305, Issue 7, pp. H987-95, 2013 (PubMed). (Sample species: Rat (Rattus)). Further details: Immunocytochemistry,Immunofluorescence,Immunohistochemistry

Webb, Cameron, Sundberg: "Fluorescence-labeled reporter gene in transgenic mice provides a useful tool for investigating cutaneous innervation." in: Veterinary pathology, Vol. 49, Issue 4, pp. 727-30, 2012 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunohistochemistry

Ying, Elpek, Vinjamoori, Zimmerman, Chu, Yan, Fletcher-Sananikone, Zhang, Liu, Wang, Ren, Zheng, Kimmelman, Paik, Lim, Perry, Jiang, Malinn, Protopopov, Colla, Xiao, Hezel, Bardeesy, Turley, Wang et al.: "PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network. ..." in: Cancer discovery, Vol. 1, Issue 2, pp. 158-69, 2012 (PubMed). Further details: Immunohistochemistry

Saatchi, Azuma, Wanchoo, Smith, Yock, Taylor, Tsao: "Three-dimensional microstructural changes in murine abdominal aortic aneurysms quantified using immunofluorescent array tomography." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 60, Issue 2, pp. 97-109, 2012 (PubMed).