Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Add to Basket
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN153417

Actin, beta (ACTB) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms
ACTA1, A, ACT5C, Ac5C, Act, Act-5C, Act5, Act5c, Actin, Actin/BAP47, Actin5C, BAP47, Bap47, CG4027, Dmel\\CG4027, M32055, T11, act, act 5C, act5C, actin, actin5C, anon-EST:fe2D2, beta-actin, beta-acti ... show more
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN153417
Quantity 0.1 mg
Price
Contact our Customer Service for availability and price in your country.
Shipping to
Immunogen The epitope recognized by this antibody maps to the N-terminus of human Beta-actinusing the numbering given in Swiss-Prot entry P60709 (GeneID 60).
Specificity Detects a single clean band at 40kD representing actin. Species Reactivity: Human and Mouse.
Cross-Reactivity Human, Mouse (Murine)
Purification Affinity Purified
Alternative Name Actin beta / ACTB
Background In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have beenidentified. The alpha actins are found in muscle tissues and are a major constituent ofthe contractile apparatus. The beta and gamma actins coexist in most cell types ascomponents of the cyto-skeleton and as mediators of internal cell motility. Beta actinsare highly conserved proteins that are involved in cell motility, structure and integrity.Beta actins are cytoplasmic proteins ubiquitously expressed in all eukaryotic cells.Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in theform of a two-stranded helix. Each actin can bind to 4 others. This antibody serves as anexcellent loading control. Alternate Names: anti-ActG antibody, anti-ActG1 antibody, anti-Actin antibody, anti-Gamma1 antibody,anti-DFNA20 antibody.
Gene ID 60, 11465
UniProt P60709
Application Notes Suggested working dilutions: immunoprecipitation 2-5 ug/mg,Western Blot 1:5,000-1:15,000
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer Tris-citrate/phosphate buffer, pH 7 to 8. Preservative: 0.09% Sodium Azide.
Preservative Sodium azide
Storage 4 °C
Watters, Kraja, Meucci et al.: "Genome-wide discovery of loci influencing chemotherapy cytotoxicity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 32, pp. 11809-14, 2004 (PubMed).

Sanue, Sinnett, Delvin et al.: "Localization and role of NPC1L1 in cholesterol absorption in human intestine." in: Journal of lipid research, Vol. 47, Issue 10, pp. 2112-20, 2006 (PubMed).

Boutz, Chawla, Stoilov et al.: "MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development." in: Genes & development, Vol. 21, Issue 1, pp. 71-84, 2007 (PubMed).

Alternatives for antigen "Actin, beta (ACTB)", type "Antibodies"
Hosts (206), (126), (21), (2), (2)
Reactivities (323), (194), (177), (73), (59), (58), (45), (31), (30), (25), (24), (19), (17), (13), (11), (6), (5), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (314), (134), (99), (69), (53), (51), (33), (20), (18), (17), (10), (4), (4), (3), (2), (2), (1), (1)
Conjugates (14), (11), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (95), (23), (12), (9), (6), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1)
Beacon